Maternal glucocorticoids do not directly mediate the effects of maternal social stress on the fetus

Y Sze, J Fernandes, ZM Kołodziejczyk… - Journal of …, 2022 - joe.bioscientifica.com
Stress during pregnancy negatively affects the fetus and increases the risk for affective
disorders in adulthood. Excess maternal glucocorticoids are thought to mediate fetal …

Comprehensive sex steroid profiling in multiple tissues reveals novel insights in sex steroid distribution in male mice

H Colldén, ME Nilsson, AK Norlén, A Landin… - …, 2022 - academic.oup.com
A comprehensive atlas of sex steroid distribution in multiple tissues is currently lacking, and
how circulating and tissue sex steroid levels correlate remains unknown. Here, we adapted …

An aggressive interaction rapidly increases brain androgens in a male songbird during the non-breeding season

C Jalabert, SL Gray, KK Soma - Journal of Neuroscience, 2024 - Soc Neuroscience
Aggression is a crucial behavior that impacts access to limited resources in different
environmental contexts. Androgens synthesized by the gonads promote aggression during …

Glucocorticoid production in lymphoid organs: acute effects of lipopolysaccharide in neonatal and adult mice

M Salehzadeh, JE Hamden, MX Li, H Bajaj… - …, 2022 - academic.oup.com
Glucocorticoids (GCs) are critical modulators of the immune system. The hypothalamic-
pituitary-adrenal (HPA) axis regulates circulating GC levels and is stimulated by endotoxins …

Isoflurane stress induces region-specific glucocorticoid levels in neonatal mouse brain

JE Hamden, KM Gray, M Salehzadeh… - Journal of …, 2022 - joe.bioscientifica.com
The profound programming effects of early life stress (ELS) on brain and behavior are
thought to be primarily mediated by adrenal glucocorticoids (GCs). However, in mice …

Neonatal Exposure to Valproate Induces Long-Term Alterations in Steroid Hormone Levels in the Brain Cortex of Prepubertal Rats

SA Kim, EH Jang, J Lee, SH Cho - International Journal of Molecular …, 2023 - mdpi.com
Valproic acid (VPA) is a known drug for treating epilepsy and mood disorders; however, it is
not recommended for pregnant women because of its possible teratogenicity. VPA affects …

Steroid profiling in human primary teeth via liquid chromatography-tandem mass spectrometry for long-term retrospective steroid measurement

RS Wu, JE Hamden, M Salehzadeh, MX Li, A Poudel… - PloS one, 2024 - journals.plos.org
Steroid hormones are important modulators of many physiological processes, and
measurements of steroids in blood, saliva, and urine matrices are widely used to assess …

Profiling of adrenal corticosteroids in blood and local tissues of mice during chronic stress

K Vagnerová, M Jágr, C Mekadim, P Ergang… - Scientific Reports, 2023 - nature.com
Stress increases plasma concentrations of corticosteroids, however, their tissue levels are
unclear. Using a repeated social defeat paradigm, we examined the impact of chronic stress …

[HTML][HTML] Glucocorticoid production in the thymus and brain: Immunosteroids and neurosteroids

M Salehzadeh, KK Soma - Brain, Behavior, & Immunity-Health, 2021 - Elsevier
Glucocorticoids (GCs) regulate a myriad of physiological systems, such as the immune and
nervous systems. Systemic GC levels in blood are often measured as an indicator of local …

Steroid profiling in brain and plasma of adult zebra finches following traumatic brain injury

SL Gray, KK Soma, KA Duncan - Journal of …, 2022 - Wiley Online Library
Traumatic brain injury (TBI) is a serious health concern and a leading cause of death.
Emerging evidence strongly suggests that steroid hormones (estrogens, androgens, and …