Amelogenesis imperfecta (AI) is one of the typical dental genetic diseases in human. It can
occur isolatedly or as part of a syndrome. Previous reports have mainly clarified the types …

Amelogenesis imperfecta (AI) is a heterogeneous group of genetic rare diseases disrupting
enamel development (Smith et al., Front Physiol, 2017a, 8, 333). The clinical enamel …

Abstract Background Mutation in Odontogenesis‐associated phosphoprotein (ODAPH) has
been reported to cause recessive hypomineralized amelogenesis imperfecta (AI) in human …

Ameloblasts responsible for enamel formation express matrix metalloproteinase 20
(MMP20), an enzyme that cleaves enamel matrix proteins, including amelogenin (AMELX) …

Amelogenesis imperfecta (AI) is a heterogeneous group of genetic rare diseases disrupting
enamel development (Smith et al., Front Physiol, 2017a, 8, 333). The clinical enamel …

Abstract Background Matrix metallopeptidase 20 (MMP20) is an evolutionarily conserved
protease that is essential for processing enamel matrix proteins during dental enamel …

Enamel forming ameloblasts move away from the dentino-enamel junction and also move
relative to each other to establish enamel shape during the secretory stage of enamel …

Objective: To identify which genes are associated with the clinical phenotype of
amelogenesis Imperfecta (AI) and to elucidate which of these genes participate in the …

Amelogenesis imperfecta (AI) refers to a group of genetic alterations of the normal structure
of the dental enamel that disturbs its clinical appearance. AI is classified as hypoplastic …

Amelogenesis imperfecta (AI) describes a heterogeneous group of developmental enamel
defects that typically have Mendelian inheritance. Exome sequencing of 10 families with …