Recent substantial evidence implicating commensal bacteria in human diseases has given
rise to a new domain in biomedical research: microbiome medicine. This emerging field …

To elucidate the role of Tau isoforms and post-translational modification (PTM) stoichiometry
in Alzheimer's disease (AD), we generated a high-resolution quantitative proteomics map of …

Precise control of plant stem cell proliferation is necessary for the continuous and
reproducible development of plant organs,. The peptide ligand CLAVATA3 (CLV3) and its …

Background: The mitochondrial calcium uniporter (mtCU) is an≈ 700-kD multisubunit
channel residing in the inner mitochondrial membrane required for mitochondrial Ca2+ …

In recent years, copy number (CN) variation has emerged as a new and significant source of
genetic polymorphisms contributing to the phenotypic diversity of populations. CN variants …

Hypoxia inducible factor (HIF) transcription factors are crucial for regulating a variety of
cellular activities in response to oxygen stress (hypoxia). In this study, we determine the …

Motivation The computational prediction of gene function is a key step in making full use of
newly sequenced genomes. Function is generally predicted by transferring annotations from …

There is considerable interest in comparing functional genomic data across species. One
goal of such work is to provide an integrated understanding of genome and phenotype …

The flavonoids, one of the largest classes of plant secondary metabolites, are found in
lineages that span the land plant phylogeny and play important roles in stress responses …

Vitellogenin (Vg), a storage protein, has been extensively studied for its egg-yolk precursor
role, and it has been suggested to be fundamentally involved in caste differences in social …