The brain is the body's control center, so when a disease affects it, the outcomes are
devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases …

Since 1992, the amyloid cascade hypothesis has played the prominent role in explaining the
etiology and pathogenesis of Alzheimer′ s disease (AD). It proposes that the deposition of …

Alzheimer's disease (AD) is characterized by senile plaques and neurodegeneration
although the neurotoxic mechanisms have not been completely elucidated. It is clear that …

Since the earliest descriptions of Alzheimer's disease (AD), many theories have been
advanced as to its cause. These include:(1) exacerbation of aging,(2) degeneration of …

A protein undergoes many types of posttranslation modification. Citrullination is one of these
modifications, where an arginine amino acid is converted to a citrulline amino acid. This …

Atypical amyloid generation, folding, aggregation and impaired clearance are characteristic
pathological features of human neurodegenerative disorders including Alzheimer's disease …

The aim of this review is to present evidence of the impact of ischemic changes in the blood–
brain barrier on the maturation of post-ischemic brain neurodegeneration with features of …

Since the inception of the human microbiome project (HMP) by the US National Institutes of
Health (NIH) in 2007 there has been a keen resurgence in our recognition of the human …

Since the earliest descriptions of the disease, senile plaques (SP) and neurofibrillary tangles
(NFT) have been regarded as the pathological 'hallmarks' of Alzheimer's disease (AD) …

Alzheimer's disease is an age-related neurodegenerative disorder with its toxicity linked to
the generation of amyloid-β peptide (Aβ). Within the Aβ sequence, there is a systemic repeat …