Epidemiological studies implicate excess ethanol ingestion as a risk factor for several
cancers and support the concept of a synergistic effect of chronic alcohol consumption and …

Folate and alcohol are dietary factors affecting the risk of cancer development in humans.
The interaction between folate status and alcohol consumption in carcinogenesis involves …

Diatoms are the dominant component of the marine phytoplankton. Several diatoms produce
secondary metabolites, namely oxylipins, with teratogenic effects on their main predators …

Background Metabolic associated fatty liver disease (MAFLD), a prevalent liver disorder
affecting one-third of the global population, encompasses a spectrum ranging from fatty liver …

Abstract ALDH1L1 (10-formyltetrahydrofolate dehydrogenase), an enzyme of folate
metabolism highly expressed in liver, metabolizes 10-formyltetrahydrofolate to produce …

Folate (vitamin B9) is a common name for a group of coenzymes that function as carriers of
chemical moieties called one-carbon groups in numerous biochemical reactions. The …

Folate, also known as vitamin B9, plays a crucial role in the one-carbon (1C) metabolism, a
conserved pathway from microbes to humans. The 1C metabolism, consisting of the folate …

Change in cell size may bring in profound impact to cell function and survival, hence the
integrity of the organs consisting of those cells. Nevertheless, how cell size is regulated …

Type 2 diabetes mellitus (T2DM) is a metabolic disease controlled by a combination of
genetic and environmental factors. The Chinese hamster, as a novel animal model of …

10-Formyltetrahydrofolate dehydrogenase (FDH), which is composed of a small N-terminal
domain (Nt-FDH) and a large C-terminal domain, is an abundant folate enzyme in the liver …