We report novel pharmaceutical cocrystal of a popular antipyretic drug paracetamol (PCA)
with coformer 5-nitroisophhthalic acid (5NIP) to improve its tabletability. The cocrystal (PCA …

A fast and simple method for the quantitative analysis of monoclinic (form I) and
orthorhombic (form II) paracetamol was developed, based on FT-Raman spectroscopy and …

We have been able to isolate and study the polymorphic form III of paracetamol using a
specially designed methodology. Our work represents the first report of a reproducible …

Controlling crystal polymorphism is crucial in the manufacturing of pharmaceuticals. In this
work, we combine experimental characterization (including online imaging, infrared and …

Paracetamol is a popular antipyretic and analgesic active pharmaceutical ingredient that is
used worldwide in the production of several millions of tablets and other dosage forms every …

In the present research, batch cooling crystallization of paracetamol from ethanol solutions is
used as a model system for exploring the utility of focused beam reflectance measurement …

Crystallization is an important separation unit operation accounting for nearly 90% of
organic molecules in the pharmaceutical and fine chemical industries. Recently, continuous …

Purpose At high relative humidity (RH), orthorhombic paracetamol (form II) crystallized from
ethanol transforms to monoclinic (form I) faster than such crystallized from the melt. The …

The effects of some crystallisation conditions on the formation of orthorhombic paracetamol
from ethanolic solution are examined when seeding technique is applied under fixed …

Paracetamol crystals often exhibit poor compressibility properties, which results in capping
issues. The Particle Size Distribution (PSD) of paracetamol was engineered to improve the …