Psoriasis is a prevalent, chronic inflammatory disease of the skin, mediated by crosstalk
between epidermal keratinocytes, dermal vascular cells, and immunocytes such as antigen …

Adipose tissue is still regarded as a principle site for lipid storage and mobilizing tissue with
an important role in the control of energy homeostasis. Additionally, adipose tissue-secreted …

Human aging is characterized by both physical and physiological frailty. A key feature of
frailty, sarcopenia is the age-associated decline in skeletal muscle mass, strength, and …

Aims/hypothesis Increased inflammation and oxidative stress are associated with insulin
resistance (IR) and metabolic disorders. Serum histidine levels are lower and are negatively …

Adipocytokines are adipocyte‐secreted hormones associated with some malignancies such
as colorectal, breast, and prostate cancer. We hypothesized that changes in the levels of …

The prevalence of obesity has increased dramatically worldwide, predisposing individuals to
an increased risk of morbidity and mortality due to cardiovascular disease and type 2 …

Obesity is an inflammatory disorder characterized by heightened activity of the innate
immune system. Innate immune activation is central to the development of obesity‐related …

Macrophages play key roles in obesity-associated pathophysiology, including inflammation,
atherosclerosis, and cancer, and processes that affect the survival-death balance of …

Adipose tissue is an active endocrine organ contributing to the regulation of multiple
metabolic pathways via self‐produced bioactive products called adipokines. These …

The ability to adapt and respond to nutrients is an ancient cellular function, conserved from
unicellular to the most complex multicellular organisms, including mammals. Mammals …