Background Multiple relapses characterise the course of illness in most patients with
schizophrenia, yet the nature of these episodes has not been extensively researched and …

Antipsychotic drugs (APDs) are best classified as typical or atypical. The distinction is based
solely on their ability to cause extrapyramidal side effects (EPS), including tardive dyskinesia …

Objective: The study was designed to evaluate the short-term efficacy and safety of
lurasidone in the treatment of acute schizophrenia. Method: Participants, who were recently …

The original definition of atypical antipsychotic drugs (APD) was drugs that are effective
against positive symptoms in schizophrenia with no or little extrapyramidal symptoms (EPS) …

Osteoporosis, a syndrome characterized by thin bones and fractures, has become more
prevalent in both women and men. Established therapies for treating this disorder consist …

Reproductive function depends upon an operational hypothalamo–pituitary–gonadal (HPG)
axis. Due to its role in determining survival versus reproductive strategies, the HPG axis is …

Purpose/Background: Antipsychotic drugs are well established to alter circulating prolactin
levels by blocking dopamine D2 receptors in the pituitary. Prolactin activates many genes …

In the last decades, the conceptualization of schizophrenia has dramatically changed,
moving from a neurodegenerative process occurring in early adult life to a …

Atypical antipsychotics (AAPs) are the drug of choice in the management of mental illnesses
by virtue of their advantage over typical antipsychotics ie least tendency of producing …

Rationale There is an unmet need in the treatment of schizophrenia for effective medications
with fewer adverse effects. Objective This study aims to evaluate the efficacy and safety of …