Simple Summary Retrospective studies of common malignancies such as head and neck
cancer often report lower incidence and/or better outcomes for patients incidentally treated …

The immune response to viral infection involves the recognition of pathogen-derived nucleic
acids by intracellular sensors, leading to type I interferon (IFN), and downstream IFN …

Summary The ATPase Family AAA Domain Containing 3A (ATAD3A), is a mitochondrial
inner membrane protein conserved in metazoans. ATAD3A has been associated with …

Only a small proportion of patients with triple-negative breast cancer benefit from immune
checkpoint inhibitor (ICI) targeting PD-1/PD-L1 signaling in combination with chemotherapy …

Pattern-recognition receptors (PRRs) are critical to recognizing endogenous and exogenous
threats to mount a protective proinflammatory innate immune response. PRRs may be …

Background Targeting mitochondrial oncoproteins presents a new concept in the
development of effective cancer therapeutics. ATAD3A is a nuclear-encoded mitochondrial …

Despite ongoing efforts to control malaria infection, progress in lowering the number of
deaths and infections appears to have stalled. The continued high incidence of malaria …

Background ATPase family AAA-domain containing protein 3A (ATAD3A) is a nuclear-
encoded mitochondrial membrane-anchored protein involved in diverse processes …

Hepatocellular carcinoma (HCC) is one of the leading causes of tumor-associated deaths
worldwide. Despite great progress in early diagnosis and multidisciplinary tumor …

The expression and subcellular localization of immune checkpoint protein PD-L1 have been
implicated to play an important role in cancer immunotherapy. In a recent paper published in …