Mesoporous silica nanoparticles for pulmonary drug delivery

A Garcia-Fernandez, F Sancenon… - Advanced Drug Delivery …, 2021 - Elsevier
Over the last years, respiratory diseases represent a clinical concern, being included among
the leading causes of death in the world due to the lack of effective lung therapies, mainly …

[HTML][HTML] Dry powder for pulmonary delivery: A comprehensive review

B Chaurasiya, YY Zhao - Pharmaceutics, 2021 - mdpi.com
The pulmonary route has long been used for drug administration for both local and systemic
treatment. It possesses several advantages, which can be categorized into physiological, ie …

[HTML][HTML] Traditional Chinese medicine combined with pulmonary drug delivery system and idiopathic pulmonary fibrosis: rationale and therapeutic potential

Y Zhang, P Lu, H Qin, Y Zhang, X Sun, X Song… - Biomedicine & …, 2021 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive pulmonary interstitial inflammatory
disease of unknown etiology, and is also a sequela in severe patients with the Coronavirus …

Inhaled drug delivery: Past, present, and future

L Yue, X Zhang, C Zhao, R Chen, X Chen, L Rao - Nano Today, 2023 - Elsevier
Inhaled drug delivery has been an emerging route for the treatment of lung diseases with
clear advantages over oral and intravenous routes. However, the delivery efficacy is affected …

Antiproliferative effects of boswellic acid-loaded chitosan nanoparticles on human lung cancer cell line A549

N Solanki, M Mehta, DK Chellappan… - Future medicinal …, 2020 - Taylor & Francis
Aim: In the present study boswellic acids-loaded chitosan nanoparticles were synthesized
using ionic gelation technique. The influence of independent variables were studied and …

Perspectives and advancements in the design of nanomaterials for targeted cancer theranostics

YY Tan, PK Yap, GLX Lim, M Mehta, Y Chan… - Chemico-biological …, 2020 - Elsevier
Cancer continues to be one of the most challenging diseases to be treated and is one of the
leading causes of deaths around the globe. Cancers account for 13% of all deaths each …

Pulmonary targeting of inhalable moxifloxacin microspheres for effective management of tuberculosis

B Vishwa, A Moin, DV Gowda, SMD Rizvi… - Pharmaceutics, 2021 - mdpi.com
In the present study, the objective was to attain a localized lung delivery of an anti-tubercular
fluoroquinolone, moxifloxacin (MXF), targeting the alveolar macrophages through a non …

Enhancing parasitic organism detection in microscopy images through deep learning and fine-tuned optimizer

Y Kumar, P Garg, MR Moudgil, R Singh, M Woźniak… - Scientific Reports, 2024 - nature.com
Parasitic organisms pose a major global health threat, mainly in regions that lack advanced
medical facilities. Early and accurate detection of parasitic organisms is vital to saving lives …

[HTML][HTML] Active tuberculosis

TN Jilani, A Avula, Z Gondal, AH Siddiqui - 2018 - europepmc.org
Objectives:< p> Summarize the etiology of active tuberculosis caused by Mycobacterium
tuberculosis.</p>< p> Describe the treatment options available for active tuberculosis.</p>< …

Solid lipid nanoparticles containing anti-tubercular drugs attenuate the Mycobacterium marinum infection

S Khatak, M Mehta, R Awasthi, KR Paudel, SK Singh… - Tuberculosis, 2020 - Elsevier
The present study aimed to formulate anti-tubercular drugs (Rifampicin, Isoniazid and
Pyrazinamide) loaded solid lipid nanoparticles (ATDs-SLNs) using microemulsion technique …