Among all existing radionuclides, only a few are of interest for therapeutic applications and
more specifically for targeted alpha therapy (TAT). From this selection, actinium-225 …

Abstract Astatine-211 (211 At, t 1/2= 7.21 h) emitting two α particles with energies of 5.87
and 7.45 MeV, can lead to a high linear energy transfer (LET= 98.84 keV/µm) and short …

The high in vivo stability of 2, 2-dihydroxymethyl-3-[18F] fluoropropyl-2-nitroimidazole ([18F]
DiFA) prompted us to evaluate neopentyl as a scaffold to prepare a radiotheranostic system …

Purpose We have developed probes for multiradionuclides radiotheranostics using RGD
peptide ([67Ga] Ga-DOTA-c [RGDf (4-I) K]([67Ga] 1) and Ga-DOTA-[211At] c [RGDf (4-At) …

A boron neutron capture therapy (BNCT) system, using boron-10-introduced agents coupled
with companion diagnostics, is anticipated as a promising cancer theranostic. Thus, this …

Osimertinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor
approved for treating non-small-cell lung cancer (NSCLC) with EGFR mutations. Genetic …

To enhance targeting efficacy in the radioimmunotherapy of disseminated cancer, several
pretargeting strategies have been developed. In pretargeted radioimmunotherapy, the tumor …

Probes for radiotheranostics could be produced by introducing radionuclides with similar
chemical characteristics into the same precursors. We recently developed an 211At-labeled …

Halogenation is widespread in Nature, as witnessed by the several thousands of naturally
occurring halogenated compounds. This review seeks to provide an overview on the …

Easy access to radioiodinated and 211At-labelled bio (macro) molecules is essential to
develop new strategies in nuclear imaging and targeted radionuclide therapy of cancers …