Cellular immune responses in the pathophysiology of preeclampsia

D Miller, K Motomura, J Galaz… - Journal of Leukocyte …, 2022 - academic.oup.com
Preeclampsia, defined as new-onset hypertension accompanied by proteinuria occurring at
20 weeks of gestation or later, is a leading cause of perinatal morbidity and mortality …

Oxidative stress in the placenta

L Myatt, X Cui - Histochemistry and cell biology, 2004 - Springer
Pregnancy is a state of oxidative stress arising from increased placental mitochondrial
activity and production of reactive oxygen species (ROS), mainly superoxide anion. The …

[HTML][HTML] Nitric oxide and reactive oxygen species in the pathogenesis of preeclampsia

K Matsubara, T Higaki, Y Matsubara… - International journal of …, 2015 - mdpi.com
Preeclampsia (PE) is characterized by disturbed extravillous trophoblast migration toward
uterine spiral arteries leading to increased uteroplacental vascular resistance and by …

Hypoxia and reoxygenation: a possible mechanism for placental oxidative stress in preeclampsia

TH Hung, GJ Burton - Taiwanese Journal of Obstetrics and Gynecology, 2006 - Elsevier
Preeclampsia is a human pregnancy-specific disorder that is diagnosed by the new
appearance of hypertension and proteinuria after 20 weeks' gestation. It is a leading cause …

Distribution of angiotensin-(1-7) and ACE2 in human placentas of normal and pathological pregnancies

G Valdés, LAA Neves, L Anton, J Corthorn, C Chacón… - Placenta, 2006 - Elsevier
This work was designed to study the expression of the vasodilator peptide angiotensin-(1-
7)[Ang-(1-7)] and its generating enzyme (ACE2) in the uteroplacental interface. Placentas …

[HTML][HTML] Role of nitric oxide in placental vascular development and function

BJ Krause, MA Hanson, P Casanello - Placenta, 2011 - Elsevier
Nitric oxide (NO) is one of the most pleiotropic signaling molecules at systemic and cellular
levels, participating in vascular tone regulation, cellular respiration, proliferation, apoptosis …

In vitro ischemia-reperfusion injury in term human placenta as a model for oxidative stress in pathological pregnancies

TH Hung, JN Skepper, GJ Burton - The American journal of pathology, 2001 - Elsevier
Oxidative stress is a prominent feature of the placenta in many complications of pregnancy,
such as preeclampsia. The cause is primarily unknown, although ischemia-reperfusion …

Acute hyperglycemia induces nitrotyrosine formation and apoptosis in perfused heart from rat

A Ceriello, L Quagliaro, M D'Amico, C Di Filippo… - Diabetes, 2002 - Am Diabetes Assoc
This study investigated coronary perfusion pressure, nitric oxide (NO) and superoxide
production, nitrotyrosine (NT) formation, and cardiac cell apoptosis in isolated hearts …

Prenatal anemia and postpartum hemorrhage risk: A systematic review and meta‐analysis

MO Omotayo, AI Abioye, M Kuyebi… - Journal of Obstetrics and …, 2021 - Wiley Online Library
Introduction Postpartum hemorrhage (PPH) has remained the leading cause of maternal
mortality. While anemia is a leading contributor to maternal morbidity, molecular, cellular …

Nitric oxide and its role during pregnancy: from ovulation to delivery

H Maul, M Longo, GR Saade… - Current pharmaceutical …, 2003 - ingentaconnect.com
Nitric oxide (NO) is a major paracrine mediator and important regulatory agent in various
female reproductive processes, such as ovulation, implantation, pregnancy maintenance …