[HTML][HTML] Implantable brain machine interfaces: first-in-human studies, technology challenges and trends

AB Rapeaux, TG Constandinou - Current opinion in biotechnology, 2021 - Elsevier
Implantable brain machine interfaces (BMIs) are now on a trajectory to go mainstream,
wherein what was once considered last resort will progressively become elective at earlier …

Neural decoding for intracortical brain–computer interfaces

Y Dong, S Wang, Q Huang, RW Berg… - Cyborg and Bionic …, 2023 - spj.science.org
Brain–computer interfaces have revolutionized the field of neuroscience by providing a
solution for paralyzed patients to control external devices and improve the quality of daily …

Wireless Battery-free and Fully Implantable Organ Interfaces

A Bhatia, J Hanna, T Stuart, KA Kasper… - Chemical …, 2024 - ACS Publications
Advances in soft materials, miniaturized electronics, sensors, stimulators, radios, and battery-
free power supplies are resulting in a new generation of fully implantable organ interfaces …

Towards clinical application of implantable brain–computer interfaces for people with late-stage ALS: medical and ethical considerations

MJ Vansteensel, E Klein, G van Thiel, M Gaytant… - Journal of …, 2023 - Springer
Individuals with amyotrophic lateral sclerosis (ALS) frequently develop speech and
communication problems in the course of their disease. Currently available augmentative …

Functional characterization of human pluripotent stem cell-derived models of the brain with microelectrode arrays

A Pelkonen, C Pistono, P Klecki, M Gómez-Budia… - Cells, 2021 - mdpi.com
Human pluripotent stem cell (hPSC)-derived neuron cultures have emerged as models of
electrical activity in the human brain. Microelectrode arrays (MEAs) measure changes in the …

Invasive brain computer interface for motor restoration in spinal cord injury: a systematic review

JJ Levett, LM Elkaim, F Niazi, MH Weber… - … : Technology at the …, 2024 - Elsevier
Study design Systematic review of the literature. Objectives In recent years, brain-computer
interface (BCI) has emerged as a potential treatment for patients with spinal cord injury …

The state of clinical trials of implantable brain–computer interfaces

KM Patrick-Krueger, I Burkhart… - Nature reviews …, 2024 - nature.com
Implanted brain–computer interfaces (iBCIs) translate brain activity recorded intracranially
into commands for virtual or physical machines to restore or rehabilitate motor, sensory or …

Pro-myelinating Clemastine administration improves recording performance of chronically implanted microelectrodes and nearby neuronal health

K Chen, F Cambi, TDY Kozai - Biomaterials, 2023 - Elsevier
Intracortical microelectrodes have become a useful tool in neuroprosthetic applications in
the clinic and to understand neurological disorders in basic neurosciences. Many of these …

Longevity and reliability of chronic unit recordings using the Utah, intracortical multi-electrode arrays

C Sponheim, V Papadourakis… - Journal of neural …, 2021 - iopscience.iop.org
Objective. Microelectrode arrays are standard tools for conducting chronic
electrophysiological experiments, allowing researchers to simultaneously record from large …

An integrated perspective for the diagnosis and therapy of neurodevelopmental disorders–From an engineering point of view

NM Hemed, NA Melosh - Advanced Drug Delivery Reviews, 2023 - Elsevier
Neurodevelopmental disorders (NDDs) are complex conditions with largely unknown
pathophysiology. While many NDD symptoms are familiar, the cause of these disorders …