Lower extremity peripheral artery disease: contemporary epidemiology, management gaps, and future directions: a scientific statement from the American Heart …

MH Criqui, K Matsushita, V Aboyans, CN Hess… - Circulation, 2021 - Am Heart Assoc
Lower extremity peripheral artery disease (PAD) affects> 230 million adults worldwide and is
associated with increased risk of various adverse clinical outcomes (other cardiovascular …

Critical limb ischemia: an expert statement

MH Shishehbor, CJ White, BH Gray, MT Menard… - Journal of the American …, 2016 - jacc.org
Critical limb ischemia (CLI), the most advanced form of peripheral artery disease, is
associated with significant morbidity, mortality, and health care resource utilization. It is also …

Restoration of brain circulation and cellular functions hours post-mortem

Z Vrselja, SG Daniele, J Silbereis, F Talpo… - Nature, 2019 - nature.com
The brains of humans and other mammals are highly vulnerable to interruptions in blood
flow and decreases in oxygen levels. Here we describe the restoration and maintenance of …

State-of-the-art methods for evaluation of angiogenesis and tissue vascularization: a scientific statement from the American Heart Association

M Simons, K Alitalo, BH Annex, HG Augustin… - Circulation …, 2015 - Am Heart Assoc
The American Heart Association makes every effort to avoid any actual or potential conflicts
of interest that may arise as a result of an outside relationship or a personal, professional, or …

Designing acellular injectable biomaterial therapeutics for treating myocardial infarction and peripheral artery disease

MJ Hernandez, KL Christman - Basic to Translational Science, 2017 - jacc.org
As the number of global deaths attributed to cardiovascular disease continues to rise, viable
treatments for cardiovascular events such as myocardial infarction or conditions like …

Radiotracer imaging allows for noninvasive detection and quantification of abnormalities in angiosome foot perfusion in diabetic patients with critical limb ischemia …

JL Alvelo, X Papademetris… - Circulation …, 2018 - Am Heart Assoc
Background: Single photon emission computed tomography (SPECT)/computed
tomography (CT) imaging allows for assessment of skeletal muscle microvascular perfusion …

SPECT and PET imaging of angiogenesis and arteriogenesis in pre-clinical models of myocardial ischemia and peripheral vascular disease

G Hendrikx, S Vöö, M Bauwens, MJ Post… - European Journal of …, 2016 - Springer
Purpose The extent of neovascularization determines the clinical outcome of coronary artery
disease and other occlusive cardiovascular disorders. Monitoring of neovascularization is …

Molecular imaging of lower extremity peripheral arterial disease: an emerging field in nuclear medicine

MR Stacy - Frontiers in Medicine, 2022 - frontiersin.org
Peripheral arterial disease (PAD) is an atherosclerotic disorder of non-coronary arteries that
is associated with vascular stenosis and/or occlusion. PAD affecting the lower extremities is …

Prognostic value of radiotracer-based perfusion imaging in critical limb ischemia patients undergoing lower extremity revascularization

TH Chou, JL Alvelo, S Janse, X Papademetris… - Cardiovascular …, 2021 - jacc.org
Objectives The purpose of this study was to evaluate the prognostic value of single-photon
emission computed tomography (SPECT)/computed tomography (CT) imaging of …

SPECT/CT imaging: a noninvasive approach for evaluating serial changes in angiosome foot perfusion in critical limb ischemia

TH Chou, SA Atway, AJ Bobbey, TP Sarac… - Advances in wound …, 2020 - liebertpub.com
Objective: To investigate the feasibility of serial radiotracer-based imaging as a noninvasive
approach for quantifying volumetric changes in microvascular perfusion within angiosomes …