Epigenetic events in mammalian germ-cell development: reprogramming and beyond

H Sasaki, Y Matsui - Nature Reviews Genetics, 2008 - nature.com
The epigenetic profile of germ cells, which is defined by modifications of DNA and
chromatin, changes dynamically during their development. Many of the changes are …

Mechanisms of germ cell specification across the metazoans: epigenesis and preformation

CG Extavour, M Akam - 2003 - journals.biologists.com
Germ cells play a unique role in gamete production, heredity and evolution. Therefore, to
understand the mechanisms that specify germ cells is a central challenge in developmental …

Direct observation of translational activation by a ribonucleoprotein granule

R Chen, W Stainier, J Dufourt, M Lagha… - Nature Cell …, 2024 - nature.com
Biomolecular condensates organize biochemical processes at the subcellular level and can
provide spatiotemporal regulation within a cell. Among these, ribonucleoprotein (RNP) …

A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary

H Lin, AC Spradling - Development, 1997 - journals.biologists.com
Germline stem cells play a pivotal role in gametogenesis; yet little is known about how they
are formed, how they divide to self-renew, and how these processes are genetically …

[图书][B] The insect ovary: ultrastructure, previtellogenic growth and evolution

J Büning - 1994 - books.google.com
This book will give an overview of insect ovaries, showing the diversities and the common
traits in egg growth processes. The idea to write this book developed while looking at the …

[HTML][HTML] Live imaging of endogenous RNA reveals a diffusion and entrapment mechanism for nanos mRNA localization in Drosophila

KM Forrest, ER Gavis - Current biology, 2003 - cell.com
Background: Localization of nanos mRNA to the posterior pole of the Drosophila embryo
directs local synthesis of Nanos protein that is essential for patterning of the anterior …

Moving messages: the intracellular localization of mRNAs

D St Johnston - Nature reviews Molecular cell biology, 2005 - nature.com
Abstract mRNA localization is a common mechanism for targeting proteins to regions of the
cell where they are required. It has an essential role in localizing cytoplasmic determinants …

Germ cells

C Wylie - Cell, 1999 - cell.com
All sexually reproducing organisms arise from gametes, sembly of pole plasm material at the
posterior pole of highly specialized cells that together initiate constructhe oocyte …

Development without germ cells: the role of the germ line in zebrafish sex differentiation

K Slanchev, J Stebler… - Proceedings of the …, 2005 - National Acad Sciences
The progenitors of the gametes, the primordial germ cells (PGCs) are typically specified
early in the development in positions, which are distinct from the gonad. These cells then …

A conserved germline multipotency program

CE Juliano, SZ Swartz, GM Wessel - Development, 2010 - journals.biologists.com
The germline of multicellular animals is segregated from somatic tissues, which is an
essential developmental process for the next generation. Although certain ecdysozoans and …