Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …

It has been known for more than 60 years, and suspected for over 100, that alveolar hypoxia
causes pulmonary vasoconstriction by means of mechanisms local to the lung. For the last …

Hydrogen sulfide (H 2 S) has been traditionally viewed as a toxic gas. It is also, however,
endogenously generated from cysteine metabolism. We attempted to assess the …

Local increases in intracellular calcium ion concentration ([Ca2+] i) resulting from activation
of the ryanodine-sensitive calcium-release channel in the sarcoplasmic reticulum (SR) of …

The dense network of capillaries composed of capillary endothelial cells (cECs) and
pericytes lies in close proximity to all neurons, ideally positioning it to sense neuron-and …

VAN ROSSUM, DU-K. HANISCH AND R. QUIRION. Neuroanatomical localization,
pharmacological characterization and functions of CGRP, related peptides and their …

ATP-sensitive potassium (KATP) channels are present in many tissues, including pancreatic
islet cells, heart, skeletal muscle, vascular smooth muscle, and brain, in which they couple …

2. Tachykinins and CGRP in primary afferent neurons 2.1. Synthesis and expression of
tachykinins 2.2. Svnthesis and exnression of CGRP 2.3. Co-localization of tachykinins and …

ATP-sensitive potassium (KATP) channels are present in the surface and internal
membranes of cardiac, skeletal, and smooth muscle cells and provide a unique feedback …

ATP-sensitive K+(K ATP) channels in vascular smooth muscle cells (VSMC) are important
targets for endogenous metabolic regulation and exogenous drug therapy. H 2 S, as a novel …