Thyroid dysfunction and diabetes mellitus are closely linked. Several studies have
documented the increased prevalence of thyroid disorders in patients with diabetes mellitus …

The most common cause of acquired thyroid dysfunction is autoimmune thyroid disease,
which is an organ-specific autoimmune disease with two presentation phenotypes …

Type 1 diabetes mellitus (T1DM) results from the autoimmune destruction of β cells of the
endocrine pancreas. Pathogenesis of T1DM is different from that of type 2 diabetes mellitus …

Autoimmune thyroid diseases (AITD) result from a dysregulation of the immune system
leading to an immune attack on the thyroid. AITD are T cell-mediated organ-specific …

Type 1 diabetes (T1D) is a chronic autoimmune disease in which destruction or damaging of
the beta-cells in the islets of Langerhans results in insulin deficiency and hyperglycemia. We …

There is increasing evidence that genome-wide association (GWA) studies represent a
powerful approach to the identification of genes involved in common human diseases. We …

Whole-genome expression profiling has created a revolution in the way we study disease
and basic biology. Since 1997, the number of published results based on an analysis of …

The protein tyrosine phosphatase (PTP) superfamily of enzymes functions in a coordinated
manner with protein tyrosine kinases to control signalling pathways that underlie a broad …

Protein tyrosine phosphorylation is a key regulatory process in virtually all aspects of cellular
functions. Dysregulation of protein tyrosine phosphorylation is a major cause of human …

Background Multiple sclerosis has a clinically significant heritable component. We
conducted a genomewide association study to identify alleles associated with the risk of …