Human beings are adept at discerning relevant information from complex systems by
processing visual information. Similarly, as scientists labor to understand the fundamental …

Mass spectrometry imaging (MSI) is a developing technique to measure the spatio-temporal
distribution of many biomolecules in tissues. Over the preceding decade, MSI has been …

A mass spectrometer is described as the smallest weighing scale ever used in the world. 1
Mass spectrometry (MS) is a unique technique that has an interdisciplinary nature, which …

Histology permits the observation of otherwise invisible structures of the internal topography
of a specimen. Although it enables the investigation of tissues at a cellular level, it is invasive …

Metabolomics is a relatively new component in systems biology that focuses on the high-
throughput characterization of small molecular metabolites in biological systems. It is widely …

Mass spectrometric imaging allows the investigation of the spatial distribution of molecules
at complex surfaces. The combination of molecular speciation with local analysis renders a …

Gold and copper nanoparticles have been widely investigated for photothermal therapy of
cancer. However, degradability and toxicity of these nanoparticles remain concerns. Here …

Imaging mass spectrometry has become a mature molecular mapping technology that is
used for molecular discovery in many medical and biological systems. While powerful by …

Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS)
combines the sensitivity and selectivity of mass spectrometry with spatial analysis to provide …

Imaging mass spectrometry (IMS) using matrix-assisted laser desorption ionization (MALDI)
is a new and effective tool for molecular studies of complex biological samples such as …