Action mechanisms of effectors in plant-pathogen interaction

S Zhang, C Li, J Si, Z Han, D Chen - International journal of molecular …, 2022 - mdpi.com
Plant pathogens are one of the main factors hindering the breeding of cash crops.
Pathogens, including oomycetes, fungus, and bacteria, secrete effectors as invasion …

NOD-like receptor-mediated plant immunity: from structure to cell death

IML Saur, R Panstruga, P Schulze-Lefert - Nature Reviews Immunology, 2021 - nature.com
Animal and plant immune systems use intracellular nucleotide-binding oligomerization
domain (NOD)-like receptors (NLRs) to detect pathogens, resulting in the activation of …

A highly differentiated region of wheat chromosome 7AL encodes a Pm1a immune receptor that recognizes its corresponding AvrPm1a effector from Blumeria …

T Hewitt, MC Müller, I Molnár, M Mascher… - New …, 2021 - Wiley Online Library
Pm1a, the first powdery mildew resistance gene described in wheat, is part of a complex
resistance (R) gene cluster located in a distal region of chromosome 7AL that has …

Long‐term and rapid evolution in powdery mildew fungi

S Kusch, J Qian, A Loos, F Kümmel… - Molecular …, 2024 - Wiley Online Library
The powdery mildew fungi (Erysiphaceae) are globally distributed plant pathogens with a
range of more than 10,000 plant hosts. In this review, we discuss the long‐and short‐term …

[HTML][HTML] Seeing is believing: Exploiting advances in structural biology to understand and engineer plant immunity

MA Outram, M Figueroa, J Sperschneider… - Current Opinion in Plant …, 2022 - Elsevier
Filamentous plant pathogens cause disease in numerous economically important crops.
These pathogens secrete virulence proteins, termed effectors, that modulate host cellular …

Surface frustration re-patterning underlies the structural landscape and evolvability of fungal orphan candidate effectors

MC Derbyshire, S Raffaele - Nature Communications, 2023 - nature.com
Pathogens secrete effector proteins to subvert host physiology and cause disease. Effectors
are engaged in a molecular arms race with the host resulting in conflicting evolutionary …

Computational Structural Genomics Unravels Common Folds and Novel Families in the Secretome of Fungal Phytopathogen Magnaporthe oryzae

K Seong, KV Krasileva - Molecular Plant-Microbe Interactions, 2021 - Am Phytopath Society
Structural biology has the potential to illuminate the evolution of pathogen effectors and their
commonalities that cannot be readily detected at the primary sequence level. Recent …

Ancient variation of the AvrPm17 gene in powdery mildew limits the effectiveness of the introgressed rye Pm17 resistance gene in wheat

MC Müller, L Kunz, S Schudel… - Proceedings of the …, 2022 - National Acad Sciences
Introgressions of chromosomal segments from related species into wheat are important
sources of resistance against fungal diseases. The durability and effectiveness of …

Effector identification in plant pathogens

AH Lovelace, S Dorhmi, MT Hulin, Y Li… - …, 2023 - Am Phytopath Society
Effectors play a central role in determining the outcome of plant− pathogen interactions. As
key virulence proteins, effectors are collectively indispensable for disease development. By …

Multiple pairs of allelic MLA immune receptor-powdery mildew AVRA effectors argue for a direct recognition mechanism

IML Saur, S Bauer, B Kracher, X Lu, L Franzeskakis… - Elife, 2019 - elifesciences.org
Nucleotide-binding domain and leucine-rich repeat (NLR)-containing proteins in plants and
animals mediate intracellular pathogen sensing. Plant NLRs typically detect strain-specific …