Helminth parasite infections are associated with a battery of immunomodulatory
mechanisms that affect all facets of the host immune response to ensure their persistence …

Deworming is rightly advocated to prevent helminth-induced morbidity. Nevertheless, in
affluent countries, the deliberate infection of patients with worms is being explored as a …

Although hatching from eggs is fundamental for nematode biology it remains poorly
understood. For animal-parasitic nematodes in particular, advancement has been slow …

Exposure to commensal and pathogenic organisms strongly influences our immune system.
Exposure to helminths was frequent before humans constructed their current highly hygienic …

In recent years, it is recognized that acquired immunity is controlled by regulatory T cell
(Treg). Since fundamental pathophysiological changes of allergy are mainly caused by …

Similar T helper (Th) 2-type immune responses are generated against different helminth
parasites, but the mechanisms that initiate Th2 immunity, and the specific immune …

Although helminth infections are characteristically associated with Th2‐mediated responses
that include the production of the prototypical cytokines IL‐4, IL‐5 and IL‐13 by CD 4+ cells …

Immune responses to gastrointestinal nematodes have been studied extensively for over 80
years and intensively investigated over the last 30–40 years. The use of laboratory models …

Asia-Pacific is a populous region with remarkable variations in socioeconomic development
and environmental exposure among countries. The prevalence rates of asthma and allergic …

Despite the tremendous progress in healthcare sectors, a number of life-threatening
infectious, inflammatory, and autoimmune diseases are continuously challenging mankind …