CD30 is a member of the tumor necrosis factor receptor superfamily. It is characteristically
expressed in certain hematopoietic malignancies, including anaplastic large cell lymphoma …

Innate immunity has been considered only to provide rapid, incomplete antimicrobial host
defense until the slower, more definitive acquired immune response develops. However …

▪ Abstract Several members of the tumor necrosis factor receptor (TNFR) family function after
initial T cell activation to sustain T cell responses. This review focuses on CD27, 4-1BB …

Interactions between co-stimulatory ligands and their receptors are crucial for the activation
of T cells, the prevention of tolerance and the development of T-cell immunity. It is now …

Background & Aims: Studies have shown that gastric T cells are increased during
Helicobacter pylori infection. The purpose of this study was to characterize the human …

Gene expression patterns can provide vital clues to the pathogenesis of neoplastic
diseases. We investigated the expression of 950 genes in Hodgkin's disease (HD) by …

Recent evidence has been accumulated to suggest that allergen-reactive type 2 helper T
cells (Th2) play a triggering role in the activation and/or recruitment of IgE antibody …

Th2 cell development is critically dependent on the presence of interleukin-4 (IL-4) at
priming. The cellular origin and the mechanisms regulating this early production of IL-4 at …

Alopecia areata (AA) is a CD8+ T-cell dependent autoimmune disease of the hair follicle
(HF) in which the collapse of HF immune privilege (IP) plays a key role. Mast cells (MCs) are …

Type 1 and Type 2: a fundamental dichotomy for all T-cell subsets Page 1 336 Type 1 and
Type 2: a fundamental dichotomy for all T-cell subsets Laura L Carter* and Richard W Duttont …