Highlights•Single cell analyses reveal cell heterogeneity, often masked at population
level.•ScRNA-Seq identifies transcriptomic signatures hallmarking distinct cell …

Acute myeloid leukemia (AML) has not benefited from innovative immunotherapies, mainly
because of the lack of actionable immune targets. Using an original proteogenomic …

When indexing large collections of short-read sequencing data, a common operation that
has now been implemented in several tools (Sequence Bloom Trees and variants, BIGSI) is …

Genetic, transcriptional, and post-transcriptional variations shape the transcriptome of
individual cells, rendering establishing an exhaustive set of reference RNAs a complicated …

Abstract Theory predicts that the sexes can achieve greater fitness if loci with sexually
antagonistic polymorphisms become linked to the sex determining loci, and this can favor …

Calling fusion genes from RNA-seq data is well established, but other transcriptional
variants are difficult to detect using existing approaches. To identify all types of variants in …

LINC00922 Accelerates the Proliferation, Migration and Invasion of Lung Cancer Via the
miRNA-204/CXCR4 Axis - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Genetic variations, including single nucleotide polymorphisms (SNPs) and structural
variations, are widely distributed in the genome, including the long noncoding RNA …

Abstract iMOKA (interactive multi-objective k-mer analysis) is a software that enables
comprehensive analysis of sequencing data from large cohorts to generate robust …

The use of RNA-sequencing technologies held a promise of improved diagnostic tools
based on comprehensive transcript sets. However, mining human transcriptome data for …