Targeting regulated cell death (RCD) with small-molecule compounds in triple-negative breast cancer: a revisited perspective from molecular mechanisms to targeted …

M Liao, R Qin, W Huang, HP Zhu, F Peng… - Journal of Hematology & …, 2022 - Springer
Triple-negative breast cancer (TNBC) is a subtype of human breast cancer with one of the
worst prognoses, with no targeted therapeutic strategies currently available. Regulated cell …

Triple-negative breast cancer: A run-through of features, classification and current therapies

M Manjunath, B Choudhary - Oncology Letters, 2021 - spandidos-publications.com
Breast cancer is the most prevalent cancer in women worldwide. Triple-negative breast
cancer (TNBC) is characterized by the lack of expression of estrogen receptor, progesterone …

A comprehensive review of artificial intelligence approaches in omics data processing: evaluating progress and challenges

AM Ali, MA Mohammed - International Journal of Mathematics, Statistics …, 2024 - ijmscs.org
The primary objective of this study is to review and assess the best available research on
omics-related artificial intelligence (AI) methods. Furthermore, it seeks to demonstrate the …

MicroRNAs involved in carcinogenesis, prognosis, therapeutic resistance, and applications in human triple-negative breast cancer

L Ding, H Gu, X Xiong, H Ao, J Cao, W Lin, M Yu, J Lin… - Cells, 2019 - mdpi.com
Triple-negative breast cancer (TNBC) is the most aggressive, prevalent, and distinct subtype
of breast cancer characterized by high recurrence rates and poor clinical prognosis, devoid …

Machine learning algorithms reveal potential miRNAs biomarkers in gastric cancer

H Azari, E Nazari, R Mohit, A Asadnia, M Maftooh… - Scientific Reports, 2023 - nature.com
Gastric cancer is the high mortality rate cancers globally, and the current survival rate is 30%
even with the use of combination therapies. Recently, mounting evidence indicates the …

[HTML][HTML] MicroRNA-9 and breast cancer

X Li, Z Zeng, J Wang, Y Wu, W Chen, L Zheng… - Biomedicine & …, 2020 - Elsevier
Breast cancer is the most common cancer in women worldwide and seriously impairs
patients' physical and mental health. Its incidence has been predicted to rise further …

Identification of diagnostic signatures and immune cell infiltration characteristics in rheumatoid arthritis by integrating bioinformatic analysis and machine-learning …

R Yu, J Zhang, Y Zhuo, X Hong, J Ye, S Tang… - Frontiers in …, 2021 - frontiersin.org
Background Rheumatoid arthritis (RA) refers to an autoimmune rheumatic disease that
imposes a huge burden on patients and society. Early RA diagnosis is critical to preventing …

New insights into the implication of epigenetic alterations in the EMT of triple negative breast cancer

N Khaled, Y Bidet - Cancers, 2019 - mdpi.com
Breast cancer is the most common cancer and leading cause of cancer death among
women worldwide, encompassing a wide heterogeneity of subtypes with different clinical …

MiR-27a-3p targeting GSK3β promotes triple-negative breast cancer proliferation and migration through Wnt/β-catenin pathway

R Wu, B Zhao, X Ren, S Wu, M Liu… - Cancer management …, 2020 - Taylor & Francis
Background Dysregulation of microRNAs (miRNAs) was found to play crucial roles in
varieties of cancers, which affect tumor proliferation and migration. MiR-27a-3p has been …

Single-molecule sensor for high-confidence detection of miRNA

KM Wijesinghe, MA Kanak, JC Harrell, S Dhakal - ACS sensors, 2022 - ACS Publications
MicroRNAs (miRNAs) play a crucial role in regulating gene expression and have been
linked to many diseases. Therefore, sensitive and accurate detection of disease-linked …