Ionic liquids: new forms of active pharmaceutical ingredients with unique, tunable properties

JL Shamshina, RD Rogers - Chemical Reviews, 2023 - ACS Publications
This Review aims to summarize advances over the last 15 years in the development of
active pharmaceutical ingredient ionic liquids (API-ILs), which make up a prospective game …

Biological activity of ionic liquids and their application in pharmaceutics and medicine

KS Egorova, EG Gordeev, VP Ananikov - Chemical reviews, 2017 - ACS Publications
Ionic liquids are remarkable chemical compounds, which find applications in many areas of
modern science. Because of their highly tunable nature and exceptional properties, ionic …

Biocompatible ionic liquids and their applications in pharmaceutics

RM Moshikur, MR Chowdhury, M Moniruzzaman… - Green …, 2020 - pubs.rsc.org
Ionic liquids (ILs) have been used as solvents or materials, or both, in many applications,
including pharmaceutics and medicine due to their exceptional properties consisting of the …

Ionic liquids in pharmaceutical industry: A systematic review on applications and future perspectives

W Zhuang, K Hachem, D Bokov, MJ Ansari… - Journal of Molecular …, 2022 - Elsevier
Ionic liquids (ILs) have demonstrated incredible potential of application in various industries
such as pharmaceutics. Appropriate utilization of ILs in the pharmaceutical industry can be a …

[HTML][HTML] Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

BJ Boyd, CAS Bergström, Z Vinarov, M Kuentz… - European Journal of …, 2019 - Elsevier
Poorly water-soluble drugs continue to be a problematic, yet important class of
pharmaceutical compounds for treatment of a wide range of diseases. Their prevalence in …

The role of ionic liquids in the pharmaceutical field: An overview of relevant applications

SN Pedro, CS R. Freire, AJD Silvestre… - International journal of …, 2020 - mdpi.com
Solubility, bioavailability, permeation, polymorphism, and stability concerns associated to
solid-state pharmaceuticals demand for effective solutions. To overcome some of these …

A review on machine learning algorithms for the ionic liquid chemical space

S Koutsoukos, F Philippi, F Malaret, T Welton - Chemical science, 2021 - pubs.rsc.org
There are thousands of papers published every year investigating the properties and
possible applications of ionic liquids. Industrial use of these exceptional fluids requires …

Ionic liquids for oral insulin delivery

A Banerjee, K Ibsen, T Brown, R Chen… - Proceedings of the …, 2018 - National Acad Sciences
With the rise in diabetes mellitus cases worldwide and lack of patient adherence to glycemia
management using injectable insulin, there is an urgent need for the development of …

Targeted modifications in ionic liquids–from understanding to design

F Philippi, T Welton - Physical Chemistry Chemical Physics, 2021 - pubs.rsc.org
Ionic liquids are extremely versatile and continue to find new applications in academia as
well as industry. This versatility is rooted in the manifold of possible ion types, ion …

Recovery and purification of ionic liquids from solutions: a review

J Zhou, H Sui, Z Jia, Z Yang, L He, X Li - RSC advances, 2018 - pubs.rsc.org
With low melting point, extremely low vapor pressure and non-flammability, ionic liquids
have been attracting much attention from academic and industrial fields. Great efforts have …