Nonhuman primate models of type 1 diabetes mellitus for islet transplantation
H Zhu, L Yu, Y He, B Wang - Journal of diabetes research, 2014 - Wiley Online Library
Islet transplantation is an attractive treatment of type 1 diabetes mellitus (T1DM). Animal
models of diabetes mellitus (DM) contribute a lot to the experimental studies of islet …
models of diabetes mellitus (DM) contribute a lot to the experimental studies of islet …
Human stem cell derived beta-like cells engineered to present PD-L1 improve transplant survival in NOD mice carrying human HLA class I
J Santini-González, R Castro-Gutierrez… - Frontiers in …, 2022 - frontiersin.org
There is a critical need for therapeutic approaches that combine renewable sources of
replacement beta cells with localized immunomodulation to counter recurrence of …
replacement beta cells with localized immunomodulation to counter recurrence of …
Anti-TCRβ mAb in Combination With Neurogenin3 Gene Therapy Reverses Established Overt Type 1 Diabetes in Female NOD Mice
A Xie, R Li, T Jiang, H Yan, H Zhang, Y Yang… - …, 2017 - academic.oup.com
Insulin-producing β cells in patients with type 1 diabetes (T1D) are destroyed by T
lymphocytes. We investigated whether targeting the T-cell receptor (TCR) with a monoclonal …
lymphocytes. We investigated whether targeting the T-cell receptor (TCR) with a monoclonal …
Reestablishing T cell tolerance by antibody-based therapy in type 1 diabetes
Y Maurice Morillon, A Martin, G Gojanovich… - Archivum Immunologiae …, 2015 - Springer
Abstract Type 1 diabetes (T1D) is an autoimmune disease in which the insulin-producing β
cells are selectively destroyed. β cell-specific T cells are considered to be the major …
cells are selectively destroyed. β cell-specific T cells are considered to be the major …
[PDF][PDF] Immunological mechanisms of pancreatic islet transplant rejection in autoimmune diabetic mice
AL Burrack - 2014 - … .digitalcollections.cuanschutz.edu
ABSTRACT Type 1 diabetes (T1D) is a T cell-dependent autoimmune disease resulting from
the destruction of insulin producing beta cells in the pancreas. Pancreatic islet …
the destruction of insulin producing beta cells in the pancreas. Pancreatic islet …
Developing clinically translatable chimerism induction protocols in a stringent murine model
J Lin - 2020 - era.library.ualberta.ca
Allogeneic hematopoietic chimerism induction via bone marrow transplantation (BMT) is
thus far the most robust method for inducing donor antigen specific tolerance to allogeneic …
thus far the most robust method for inducing donor antigen specific tolerance to allogeneic …
[PDF][PDF] 同種異系膵島移植におけるc-Fos/Activator protein-1 阻害による免疫抑制効果に関する研究
吉田雅 - 2015 - eprints.lib.hokudai.ac.jp
2. 吉田雅, 山下健一郎, 渡辺正明, 腰塚靖之, 蔵谷大輔, 小倉正臣, 後藤了一, 若山顕治, 柴崎晋,
蒲池浩文, 尾崎倫孝, 松下通明, 藤堂省. マウス膵島移植における新規 AP-1 阻害剤 T-5224 …
蒲池浩文, 尾崎倫孝, 松下通明, 藤堂省. マウス膵島移植における新規 AP-1 阻害剤 T-5224 …