Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …

Exosomes are a subset of tiny extracellular vesicles manufactured by all cells and are
present in all body fluids. They are produced actively in tumor cells, which are released and …

Cancer-derived exosomes are considered a major driver of cancer-induced pre-metastatic
niche formation at foreign sites, but the mechanisms remain unclear. Here, we show that …

Abstract Background Cancer associated fibroblasts (CAFs) are key stroma cells that play
dominant roles in tumor progression. However, the CAFs-derived molecular determinants …

Sarcomas are heterogeneous and clinically challenging soft tissue and bone cancers.
Although constituting only 1% of all human malignancies, sarcomas represent the second …

Tumors are not isolated entities, but complex systemic networks involving cell-cell
communication between transformed and non-transformed cells. The milieu created by …

Abstract N 6-methyladenosine (m6A) modification is an important mechanism in miRNA
processing and maturation, but the role of its aberrant regulation in human diseases …

Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Exosomes play an important role in intercellular communication and metastatic progression
of hepatocellular carcinoma (HCC). However, cellular communication between …

Exosomes, known as nanometer‐sized vesicles (30–200 nm), are secreted by many types of
cells. Cancer‐derived exosomes have great potential to be biomarkers for early clinical …