Critical enzyme reactions in aromatic catabolism for microbial lignin conversion

E Erickson, A Bleem, E Kuatsjah, AZ Werner… - Nature Catalysis, 2022 - nature.com
The application of microbes to valorize aromatic compounds derived from the abundant
plant biopolymer lignin is a rapidly developing area of research that may ultimately enable …

Bacterial valorization of lignin: strains, enzymes, conversion pathways, biosensors, and perspectives

S Lee, M Kang, JH Bae, JH Sohn… - … in bioengineering and …, 2019 - frontiersin.org
Lignin, an aromatic polymer found in plants, has been studied for years in many biological
fields. Initially, when biofuel was produced from lignocellulosic biomass, lignin was regarded …

Lignin conversion to β-ketoadipic acid by Pseudomonas putida via metabolic engineering and bioprocess development

AZ Werner, WT Cordell, CW Lahive, BC Klein… - Science …, 2023 - science.org
Bioconversion of a heterogeneous mixture of lignin-related aromatic compounds (LRCs) to a
single product via microbial biocatalysts is a promising approach to valorize lignin. Here …

Bioprocess development for muconic acid production from aromatic compounds and lignin

D Salvachúa, CW Johnson, CA Singer, H Rohrer… - Green …, 2018 - pubs.rsc.org
Muconic acid (MA) is a bio-based platform chemical that can be converted into the
commodity petrochemical building blocks adipic acid or terephthalic acid, or used in …

Engineering glucose metabolism for enhanced muconic acid production in Pseudomonas putida KT2440

GJ Bentley, N Narayanan, RK Jha, D Salvachúa… - Metabolic …, 2020 - Elsevier
Pseudomonas putida KT2440 has received increasing attention as an important biocatalyst
for the conversion of diverse carbon sources to multiple products, including the olefinic …

Bacterial enzymes for lignin depolymerisation: new biocatalysts for generation of renewable chemicals from biomass

TDH Bugg, JJ Williamson, GMM Rashid - Current opinion in chemical …, 2020 - Elsevier
The conversion of polymeric lignin from plant biomass into renewable chemicals is an
important unsolved problem in the biorefinery concept. This article summarises recent …

Translating new synthetic biology advances for biosensing into the earth and environmental sciences

I Del Valle, EM Fulk, P Kalvapalle, JJ Silberg… - Frontiers in …, 2021 - frontiersin.org
The rapid diversification of synthetic biology tools holds promise in making some classically
hard-to-solve environmental problems tractable. Here we review longstanding problems in …

Advances and prospects of phenolic acids production, biorefinery and analysis

E Valanciene, I Jonuskiene, M Syrpas, E Augustiniene… - Biomolecules, 2020 - mdpi.com
Biotechnological production of phenolic acids is attracting increased interest due to their
superior antioxidant activity, as well as other antimicrobial, dietary, and health benefits. As …

Outer membrane vesicles catabolize lignin-derived aromatic compounds in Pseudomonas putida KT2440

D Salvachúa, AZ Werner, I Pardo… - Proceedings of the …, 2020 - National Acad Sciences
Lignin is an abundant and recalcitrant component of plant cell walls. While lignin
degradation in nature is typically attributed to fungi, growing evidence suggests that bacteria …

Microbial hosts for metabolic engineering of lignin bioconversion to renewable chemicals

TDH Bugg, JJ Williamson, F Alberti - Renewable and Sustainable Energy …, 2021 - Elsevier
This review discusses the use of engineered microbes for bioconversion of lignin from plant
biomass to produce renewable chemicals. Existing bacterial hosts for lignin bioconversion …