Deoxycholic Acid (DCA), which is an FDA-approved compound for the reduction of
submental fat, has evolved through an unanticipated and surprising sequence of events …

Engineered nanoparticles are advantageous for biotechnology applications including
biomolecular sensing and delivery. However, testing compatibility and function of …

Berberine (BBR) is a natural alkaloid with multiple biotical effects that has potential as a
treatment for fatty liver hemorrhagic syndrome (FLHS). However, the mechanism underlying …

Excess fat accumulation is not only associated with metabolic diseases but also negatively
impacts physical appearance and emotional well-being. Bile acid, the body's natural …

Black tea (BT), the most consumed tea worldwide, can alleviate hyperlipidemia which is a
serious threat to human health. However, the quality of summer BT is poor. It was improved …

Spiral microfluidic-based devices play an important role in particle separation and
concentration which is essential for many biomedical, chemical, and environmental …

Multi‐functional polymer nanoparticles have been widely utilized to improve cellular uptake
and enhance therapeutic efficacy. In this study, it is hypothesized that the cellular uptake of …

Maintaining a balanced bile acids (BAs) metabolism is essential for lipid and cholesterol
metabolism, as well as fat intake and absorption. The development of obesity may be …

Solubilized deoxycholic acid has been FDA-approved and used commercially for local fat
reduction. However, injection site reactions, commonly bruising and swelling, have limited …

Excess calories are stored as triacylglycerols (TAG) and cholesteryl esters (CE) in lipid
droplets (LD), and during obesity, LD expansion occurs. X-ray scattering of adipose tissue …