[HTML][HTML] Recent advances in vasoactive intestinal peptide physiology and pathophysiology: focus on the gastrointestinal system

M Iwasaki, Y Akiba, JD Kaunitz - F1000Research, 2019 - ncbi.nlm.nih.gov
Vasoactive intestinal peptide (VIP), a gut peptide hormone originally reported as a
vasodilator in 1970, has multiple physiological and pathological effects on development …

Targeting VIP and PACAP receptor signaling: new insights into designing drugs for the PACAP subfamily of receptors

J Lu, SJ Piper, P Zhao, LJ Miller, D Wootten… - International journal of …, 2022 - mdpi.com
Pituitary Adenylate Cyclase-Activating Peptide (PACAP) and Vasoactive Intestinal Peptide
(VIP) are neuropeptides involved in a diverse array of physiological and pathological …

[HTML][HTML] Vasoactive intestinal polypeptide plays a key role in the microbial-neuroimmune control of intestinal motility

X Bai, G De Palma, E Boschetti, Y Nishiharo… - Cellular and molecular …, 2024 - Elsevier
Background & Aims Although chronic diarrhea and constipation are common, the treatment
is symptomatic because their pathophysiology is poorly understood. Accumulating evidence …

Antibiotic exposure postweaning disrupts the neurochemistry and function of enteric neurons mediating colonic motor activity

LY Hung, P Parathan, P Boonma… - American Journal …, 2020 - journals.physiology.org
The period during and immediately after weaning is an important developmental window
when marked shifts in gut microbiota can regulate the maturation of the enteric nervous …

β-Patchoulene Ameliorates Water Transport and the Mucus Barrier in 5-Fluorouracil-Induced Intestinal Mucositis Rats via the cAMP/PKA/CREB Signaling Pathway

J Wu, Y Gan, H Luo, N Xu, L Chen, M Li… - Frontiers in …, 2021 - frontiersin.org
Intestinal mucositis (IM) is the main side effect observed in patients who receive cancer
chemotherapy. The characteristics of ulceration, vomiting, and severe diarrhea cause …

Spexin enhances bowel movement through activating L-type voltage-dependent calcium channel via galanin receptor 2 in mice

C Lin, M Zhang, T Huang, L Yang, H Fu, L Zhao… - Scientific reports, 2015 - nature.com
A novel neuropeptide spexin was found to be broadly expressed in various endocrine and
nervous tissues while little is known about its functions. This study investigated the role of …

Nitric oxide regulates estrus cycle dependent colonic motility in mice

GK Balasuriya, SS Nugapitiya, EL Hill-Yardin… - Frontiers in …, 2021 - frontiersin.org
Women are more susceptible to functional bowel disorders than men and the severity of
their symptoms such as diarrhea, constipation, abdominal pain and bloating changes over …

Quantitative Spatial Analysis of Neuroligin-3 mRNA Expression in the Enteric Nervous System Reveals a Potential Role in Neuronal–Glial Synapses and Reduced …

M Herath, E Cho, U Marklund, AE Franks, JC Bornstein… - Biomolecules, 2023 - mdpi.com
Mutations in the Neuroligin-3 (Nlgn3) gene are implicated in autism spectrum disorder
(ASD) and gastrointestinal (GI) dysfunction, but cellular Nlgn3 expression in the enteric …

The Probiotic Combination of Lacticaseibacillus paracasei JY062 and Lactobacillus gasseri JM1 Alleviates Gastrointestinal Motility Disorder via Improving Gut …

S Cheng, H Li, Y Ding, J Huo, Y Zheng, Y Jiang… - Nutrients, 2023 - mdpi.com
Probiotics have received wide attention as a potential way to alleviate gastrointestinal (GI)
motility disorders. Herein, we investigated the effects of Lacticaseibacillus paracasei JY062 …

Expression and localization of VPAC1, the major receptor of vasoactive intestinal peptide along the length of the intestine

D Jayawardena, G Guzman, RK Gill… - American Journal …, 2017 - journals.physiology.org
Vasoactive intestinal peptide (VIP) is an endogenous neuropeptide with a broad array of
physiological functions in many organs including the intestine. Its actions are mediated via G …