Research Progress on Glycolysis Mechanism of Psoriasis

L Wei, B Zhang, Y Tu, A Liu - Psoriasis: Targets and Therapy, 2024 - Taylor & Francis
Psoriasis is a chronic inflammatory disease with a complex pathogenesis. Hyperplasia of
glycolytic-dependent epidermal keratinocytes (KCs) is a new hallmark of psoriasis …

Skin deep: Epithelial cell metabolism and chronic skin inflammation

ER Solis, JM Jameson - Immunity, 2024 - Elsevier
Skin inflammation is potentiated by coordinated epithelial and immune cell metabolism. In
this issue of Immunity, Subudhi and Konieczny et al. delineate how HIF1α regulates …

[HTML][HTML] Stiffness-dependent LOX regulation via HIF-1 drives extracellular matrix modifications in psoriasis

P Balsini, P Weinzettl, D Samardzic, N Zila… - Journal of Investigative …, 2024 - Elsevier
Psoriasis is a common chronic inflammatory skin disease characterized by a thickened
epidermis with elongated rete ridges and massive immune cell infiltration. It is currently …

Impact of 26 Skin Diseases on the Risk of Non-Small Cell Lung Cancer: A Mendelian Randomization Study Using FinnGen R11 Data

X Li, H Li - medRxiv, 2024 - medrxiv.org
Purpose To determine whether genetic predisposition to various skin diseases influences
the risk of non-small cell lung cancer (NSCLC) through Mendelian randomization (MR) …

Metabolic Stress expands Polyfunctional, Proinflammatory Th17 cells in Psoriatic Arthritis, where there is IL‐23‐independent IL‐17 production

CB Stober, L Ellis, JC Goodall, M Veldhoen… - Arthritis & … - Wiley Online Library
Objective Genetic associations and blockade of the interleukin‐23/IL‐17 axis with
monoclonal antibodies support a role for this pathway in psoriatic arthritis (PsA). This study …

[HTML][HTML] Advances in the genetics and immunology of psoriasis

A Leung, G Marquez-Grap… - IFPA-WPPAC …, 2024 - conferences.medicom-publishers …
Psoriasis is a chronic, immune-mediated skin condition characterised by keratinocyte
hyperproliferation and T cell activation. Prior research has revealed environmental and …