Summary of information on the effects of ionizing and non-ionizing radiation on cytochrome P450 and other drug metabolizing enzymes and transporters

S Rendic, F Peter Guengerich - Current Drug Metabolism, 2012 - ingentaconnect.com
The present paper is an update of data on the effects of ionizing radiation (γ-rays, X-rays,
high energy UV, fast neutron) caused by environmental pollution or clinical treatments and …

Effects of radiation on drug metabolism: a review

X Li, J Yang, Y Qiao, Y Duan, Y Xin… - Current Drug …, 2019 - ingentaconnect.com
Background: Radiation is the fourth most prevalent type of pollution following the water, air
and noise pollution. It can adversely affect normal bodily functions. Radiation alters the …

[PDF][PDF] γ 射线辐射对大鼠肝药物代谢酶CYP1A2, CYP2C9 和CYP2D6 蛋白表达及药物代谢活性的影响

董航, 张海晖, 窦桂芳, 孟志云, 叶彤… - 中国药理学与毒 …, 2021 - cjpt.magtechjournal.com
目的研究特定剂量γ 射线辐射对大鼠肝细胞色素P450 酶亚型CYP1A2, CYP2C9 和CYP2D6
蛋白表达和药物代谢活性水平的影响. 方法大鼠施以总剂量6 Gy, 剂量率68.34 cGy· min-1 …

Regulation of X-ray irradiation on the activity and expression levels of CYP1A2 and CYP2E1 in rats

XY Li, N Qu, XJ Wang, JX Yang, YY Xin… - Frontiers in …, 2020 - frontiersin.org
The objective of this study was to investigate the regulation of X-ray irradiation and its effect
on the activity and protein and mRNA expression levels of CYP1A2 and CYP2E1 in rats …

Effect of X‐ray irradiation on pharmacokinetics of irinotecan hydrochloride and expression of CES 1 and CYP 3A1 in rats

Q Yijie, W Xuejun, X Yuanyao… - Fundamental & …, 2019 - Wiley Online Library
Concurrent chemoradiation with irinotecan hydrochloride (CPT‐11) is accepted for cancer
treatment. However, the effects of X‐ray irradiation on chemotherapeutics in the plasma …

[HTML][HTML] 辐射影响药物代谢的研究进展

乔一杰, 辛元尧, 周雪姣, 杨梦, 李向阳 - 药学学报, 2017 - html.rhhz.net
辐射为继水, 大气, 噪音污染之后的第四大污染, 严重危害人体健康. 辐射主要来自医用射线,
工业用射线, 核废物和大气紫外线等, 其存在的广泛性引起人们对辐射损伤效应及其机制的广泛 …

A review of radiation impact on drug metabolism

YJ Qiao, XY Li, YY Xin, XJ Zhou, M Yang - Yaoxue Xuebao, 2017 - elibrary.ru
The radiation is regarded as the fourth biggest pollution following the water, air and noise
pollution, which generates a broad impact on human physiology and healthy. The radiation …