Obstructive sleep apnoea heterogeneity and cardiovascular disease
Obstructive sleep apnoea (OSA), characterized by recurrent periods of upper airway
obstruction and intermittent hypoxaemia, is prevalent in patients with cardiovascular disease …
obstruction and intermittent hypoxaemia, is prevalent in patients with cardiovascular disease …
Phenotypic approaches to obstructive sleep apnoea–new pathways for targeted therapy
DJ Eckert - Sleep medicine reviews, 2018 - Elsevier
People develop obstructive sleep apnoea (OSA) for different reasons. The ability to
understand these reasons, easily identify them in individual patients, and develop therapies …
understand these reasons, easily identify them in individual patients, and develop therapies …
Phenotypes in obstructive sleep apnea: a definition, examples and evolution of approaches
AV Zinchuk, MJ Gentry, J Concato, HK Yaggi - Sleep medicine reviews, 2017 - Elsevier
Obstructive sleep apnea (OSA) is a complex and heterogeneous disorder and the apnea
hypopnea index alone can not capture the diverse spectrum of the condition. Enhanced …
hypopnea index alone can not capture the diverse spectrum of the condition. Enhanced …
Personalized management approach for OSA
JC Carberry, J Amatoury, DJ Eckert - Chest, 2018 - Elsevier
OSA is a heterogeneous disorder. If left untreated, it has major health, safety, and economic
consequences. In addition to varying levels of impairment in pharyngeal anatomy …
consequences. In addition to varying levels of impairment in pharyngeal anatomy …
Polysomnographic phenotypes and their cardiovascular implications in obstructive sleep apnoea
Background Obstructive sleep apnoea (OSA) is a heterogeneous disorder, and improved
understanding of physiologic phenotypes and their clinical implications is needed. We …
understanding of physiologic phenotypes and their clinical implications is needed. We …
More than the sum of the respiratory events: personalized medicine approaches for obstructive sleep apnea
Traditionally, the presence and severity of obstructive sleep apnea (OSA) have been defined
by the apnea–hypopnea index (AHI). Continuous positive airway pressure is generally first …
by the apnea–hypopnea index (AHI). Continuous positive airway pressure is generally first …
Quantifying the arousal threshold using polysomnography in obstructive sleep apnea
Abstract Study Objectives Precision medicine for obstructive sleep apnea (OSA) requires
noninvasive estimates of each patient's pathophysiological “traits.” Here, we provide the first …
noninvasive estimates of each patient's pathophysiological “traits.” Here, we provide the first …
Upper airway collapsibility (Pcrit) and pharyngeal dilator muscle activity are sleep stage dependent
Abstract Study Objectives: An anatomically narrow/highly collapsible upper airway is the
main cause of obstructive sleep apnea (OSA). Upper airway muscle activity contributes to …
main cause of obstructive sleep apnea (OSA). Upper airway muscle activity contributes to …
Clinical phenotypes and comorbidity in European sleep apnoea patients
T Saaresranta, J Hedner, MR Bonsignore, RL Riha… - PloS one, 2016 - journals.plos.org
Background Clinical presentation phenotypes of obstructive sleep apnoea (OSA) and their
association with comorbidity as well as impact on adherence to continuous positive airway …
association with comorbidity as well as impact on adherence to continuous positive airway …
Obstructive sleep apnea without obesity is common and difficult to treat: evidence for a distinct pathophysiological phenotype
EL Gray, DK McKenzie, DJ Eckert - Journal of Clinical Sleep …, 2017 - jcsm.aasm.org
Study Objectives: To determine the proportion and physiological characteristics of nonobese
patients with obstructive sleep apnea (OSA) and their response to prescribed therapy …
patients with obstructive sleep apnea (OSA) and their response to prescribed therapy …