[HTML][HTML] Influence of cholesterol on cancer progression and therapy

SS Mayengbam, A Singh, AD Pillai, MK Bhat - Translational oncology, 2021 - Elsevier
Cholesterol is a fundamental molecule necessary for the maintenance of cell structure and is
vital to various normal biological functions. It is a key factor in lifestyle-related diseases …

Epidemiology of Helicobacter pylori and CagA-Positive Infections and Global Variations in Gastric Cancer

JY Park, D Forman, LA Waskito, Y Yamaoka… - Toxins, 2018 - mdpi.com
Gastric cancer is a major health burden and is the fifth most common malignancy and the
third most common cause of death from cancer worldwide. Development of gastric cancer …

Probiotic Lactobacillus spp. Act Against Helicobacter pylori-induced Inflammation

YH Chen, WH Tsai, HY Wu, CY Chen, WL Yeh… - Journal of clinical …, 2019 - mdpi.com
The bacterial species, Helicobacter pylori, is associated with several gastrointestinal
diseases, and poses serious health threats owing to its resistance to antibiotics …

Simvastatin induces cell cycle arrest and inhibits proliferation of bladder cancer cells via PPARγ signalling pathway

G Wang, R Cao, Y Wang, G Qian, HC Dan, W Jiang… - Scientific reports, 2016 - nature.com
Simvastatin is currently one of the most common drugs for old patients with hyperlipidemia,
hypercholesterolemia and atherosclerotic diseases by reducing cholesterol level and anti …

Weighted gene co-expression network analysis and connectivity map identifies lovastatin as a treatment option of gastric cancer by inhibiting HDAC2

L Zhang, W Kang, X Lu, S Ma, L Dong, B Zou - Gene, 2019 - Elsevier
Objective This study aimed to identifying and validating therapeutic compounds which might
have positive effects on patients with gastric cancer (GC) based on weighted gene co …

Gut Commensal Parabacteroides goldsteinii MTS01 Alters Gut Microbiota Composition and Reduces Cholesterol to Mitigate Helicobacter pylori-Induced …

CH Lai, TL Lin, MZ Huang, SW Li, HY Wu… - Frontiers in …, 2022 - frontiersin.org
Helicobacter pylori infection is closely associated with various gastrointestinal diseases and
poses a serious threat to human health owing to its increasing antimicrobial resistance. H …

Targeting cholesterol metabolism in cancer: from molecular mechanisms to therapeutic implications

J Lu, S Chen, X Bai, M Liao, Y Qiu, LL Zheng… - Biochemical …, 2023 - Elsevier
Cholesterol is an essential component of cell membranes and helps to maintain their
structure and function. Abnormal cholesterol metabolism has been linked to the …

Aspirin, metformin, and statin use on the risk of gastric cancer: A nationwide population‐based cohort study in Korea with systematic review and meta‐analysis

SI Seo, CH Park, TJ Kim, CS Bang, JY Kim… - Cancer …, 2022 - Wiley Online Library
Abstract Background/Aims Although several chemopreventive drugs against gastric cancer
have been proposed, their effects have not been fully evaluated. We examined the impacts …

Nationwide cohort study: cholesterol level is inversely related with the risk of gastric cancer among postmenopausal women

JH Lim, CM Shin, K Han, J Yoo, EH Jin, YJ Choi… - Gastric Cancer, 2022 - Springer
Background Recent studies showed inverse relationship between hypercholesterolemia
and the risk of gastric cancer, especially among male. However evidence among female is …

Association between statins' exposure with incidence and prognosis of gastric cancer: an updated meta‐analysis

D Lou, R Fu, L Gu, H Su, L Guan - Expert Review of Clinical …, 2022 - Taylor & Francis
Background and aims Previous research has revealed the role of statins in cancer
prevention and treatment. This study aimed to determine the relationship between statins' …