[HTML][HTML] Biology and treatment of Richter transformation

A Condoluci, D Rossi - Frontiers in Oncology, 2022 - frontiersin.org
Richter transformation (RT), defined as the development of an aggressive lymphoma on a
background of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) …

[HTML][HTML] Revisiting Richter transformation in the era of novel CLL agents

A Petrackova, P Turcsanyi, T Papajik, E Kriegova - Blood Reviews, 2021 - Elsevier
Richter transformation (RT) is the development of aggressive lymphoma–most frequently
diffuse large B-cell lymphoma (DLBCL) and rarely Hodgkin lymphoma (HL)–arising on the …

Venetoclax plus dose-adjusted R-EPOCH for Richter syndrome

MS Davids, KA Rogers, S Tyekucheva… - Blood, The Journal …, 2022 - ashpublications.org
Richter syndrome (RS) of chronic lymphocytic leukemia (CLL) is typically chemoresistant,
with a poor prognosis. We hypothesized that the oral Bcl-2 inhibitor venetoclax could …

Autologous and allogeneic hematopoietic cell transplantation for diffuse large B-cell lymphoma–type Richter syndrome

AF Herrera, KW Ahn, C Litovich, Y Chen… - Blood …, 2021 - ashpublications.org
Richter syndrome (RS) represents a transformation from chronic lymphocytic leukemia/small
lymphocytic lymphoma (CLL/SLL) to aggressive lymphoma, most commonly diffuse large B …

Emerging therapies for the management of Richter transformation

E Smyth, TA Eyre, CY Cheah - Journal of Clinical Oncology, 2023 - ingentaconnect.com
Richter transformation (RT) refers to the development of an aggressive lymphoma in patients
with underlying chronic lymphocytic leukemia/small lymphocytic lymphoma. Aside from a …

Outcomes of Richter's transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL): an analysis of the SEER database

R Elnair, M Ellithi, A Kallam, V Shostrom… - Annals of hematology, 2021 - Springer
Richter's transformation (RT) is a rare complication arising in patients with chronic
lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and is associated with an …

Practical management of Richter transformation in 2023 and beyond

CE Ryan, MS Davids - … Society of Clinical Oncology Educational Book, 2023 - ascopubs.org
While the past decade has witnessed unprecedented progress for patients with chronic
lymphocytic leukemia (CLL), outcomes for patients with Richter transformation (RT) remain …

From genetics to therapy: Unraveling the complexities of Richter transformation in chronic lymphocytic leukemia

P Abrisqueta, F Nadeu, J Bosch-Schips… - Cancer Treatment …, 2023 - Elsevier
Richter transformation (RT) refers to the progression of chronic lymphocytic leukemia, the
most prevalent leukemia among adults, into a highly aggressive lymphoproliferative …

[HTML][HTML] Clonal evolution of high-risk chronic lymphocytic leukemia: A contemporary perspective

M Kwok, CJ Wu - Frontiers in oncology, 2021 - frontiersin.org
Clonal evolution represents the natural process through which cancer cells continuously
search for phenotypic advantages that enable them to develop and expand within …

Novel approaches for the treatment of patients with Richter's syndrome

A Iannello, S Deaglio, T Vaisitti - Current Treatment Options in Oncology, 2022 - Springer
Opinion statement In the last 10–15 years, the way to treat cancers has dramatically
changed towards precision medicine approaches. These treatment options are mainly …