Circadian disruption is pervasive and can occur at multiple organizational levels,
contributing to poor health outcomes at individual and population levels. Evidence points to …

Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the
circadian rhythms that synchronize physiological and behavioural functions in humans. The …

The daily alternation between sleep and wakefulness is one of the most dominant features
of our lives and is a manifestation of the intrinsic 24 h rhythmicity underlying almost every …

Background Circadian disturbance is a common nonmotor complaint in Parkinson's disease
(PD). The molecular basis underlying circadian rhythm in PD is poorly understood …

The circadian system is responsible for internal functions and regulation of the organism
according to environmental cues (zeitgebers). Circadian rhythm dysregulation or …

Disruptions of circadian rhythms and sleep cycles are common among neurodegenerative
diseases and can occur at multiple levels. Accumulating evidence reveals a bidirectional …

Humans and other mammalian species possess an endogenous circadian clock system that
has evolved in adaptation to periodically reoccurring environmental changes and drives …

Circadian rhythms oscillate throughout a 24-h period and impact many physiological
processes and aspects of daily life, including feeding behaviors, regulation of the sleep …

Autonomic dysfunction and frailty are two common and complex geriatric syndromes. Their
prevalence increases with age and they have similar negative health outcomes. In PubMed …

The nearly ubiquitous expression of endogenous 24 h oscillations known as circadian
rhythms regulate the timing of physiological functions in the body. These intrinsic rhythms …