Malaria vaccine development has rapidly advanced in the past decade. The very first phase
3 clinical trial of the RTS, S vaccine was completed with over 15,000 African infants and …

Malaria control relies heavily on the use of anti-malarial drugs and insecticides against
malaria parasites and mosquito vectors. Drug and insecticide resistance threatens the …

Malaria infections remain a serious global health problem in the world, particularly among
children and pregnant women in Sub-Saharan Africa. Moreover, malaria control and …

In this paper, we developed a novel deterministic coupled model tying together the effects of
within-host and population level dynamics on malaria transmission dynamics. We develop …

Background Malaria and helminths diseases are co-endemic in most parts of sub-Saharan
Africa. Immune responses from each of these pathogens interact, and these interactions may …

The pathophysiology of severe falciparum malaria involves a complex interaction between
the host, parasite, and gut microbes. In this review, we focus on understanding parasite …

Vaccines that target Plasmodium falciparum gametocytes have the potential to reduce
malaria transmission and are thus attractive targets for malaria control. However, very little is …

Introduction The diagnosis of infectious reservoir in malaria (gametocytes) is necessary,
especially in low density infections and asymptomatic malaria patients. The gametocyte …

Background Antigametocyte-specific immune responses may regulate Plasmodium
falciparum gametocyte density, providing the rationale for pursuing transmission-blocking …

Abstract Purpose of Review Malaria transmission depends on the development and survival
in humans of mature sexual stage parasites, known as gametocytes which further develop …