Collagen is the oldest and most abundant extracellular matrix protein that has found many
applications in food, cosmetic, pharmaceutical, and biomedical industries. First, an overview …

The advent of nanotechnology, and the need to understand the chemical composition at the
nanoscale, has stimulated the convergence of IR and Raman spectroscopy with scanning …

An analytical technique operating at the nanoscale must be flexible regarding variable
experimental conditions while ideally also being highly specific, extremely sensitive, and …

For load-bearing orthopaedic applications, metal implants having an interconnected pore
structure exhibit the potential to facilitate bone ingrowth and the possibility for reducing the …

This feature review provides an overview of the state-of the art and recent developments in
tip-enhanced Raman spectroscopy (TERS), in-depth information about the different …

Raman spectroscopy can detect conformational changes in collagen structures and these
findings are reviewed in this article. More specifically, some progressive diseases are mainly …

The vibrational modes of molecules provide an intrinsic contrast mechanism for identifying
components in cells, tissues, and organisms. When excited by a laser, Raman scattered …

This study demonstrates that spectral fingerprint patterns for a weakly scattering biological
sample can be obtained reproducibly and reliably with tip-enhanced Raman spectroscopy …

Amyloid fibrils are known to be responsible for diseases such as Alzheimer's disease. A
detailed insight into the structure of amyloid fibrils is fundamental since it is not yet …

Fibrosis is a consequence of the pathological remodeling of extracellular matrix (ECM)
structures in the connective tissue of an organ. It is often caused by chronic inflammation …