The glial cell of the peripheral nervous system (PNS), the Schwann cell (SC), counts among
the most multifaceted cells of the body. During development, SCs secure neuronal survival …

The gut microbiota has emerged as an environmental factor that modulates the development
of the central nervous system (CNS) and the enteric nervous system (ENS). Before obtaining …

Background Diet-induced obesity (DIO) is a significant health concern which has been
linked to structural and functional changes in the gut microbiota. Exercise (Ex) is effective in …

Lewy pathology affects the gastrointestinal tract in Parkinson's disease (PD) and data from
recent genetic studies suggest a link between PD and gut inflammation. We therefore …

The microbiota-gut-brain axis or simple gut-brain axis (GBA) is a complex and interactive
bidirectional communication network linking the gut to the brain. Alterations in the …

The gastrointestinal tract contains its own set of intrinsic neuroglial circuits—the enteric
nervous system (ENS)—which detects and responds to diverse signals from the …

Enteric glia are a unique class of peripheral glial cells within the gastrointestinal tract. Major
populations of enteric glia are found in enteric ganglia in the myenteric and submucosal …

A large and expending body of evidence indicates that the gut-brain axis likely plays a
crucial role in neurological diseases, including multiple sclerosis (MS). As a whole, the gut …

Enteric glial cells are vital for the autonomic control of gastrointestinal homeostasis by the
enteric nervous system. Several different functions have been assigned to enteric glial cells …

At the most fundamental level, the bowel facilitates absorption of small molecules, regulates
fluid and electrolyte flux, and eliminates waste. To successfully coordinate this complex …