Sulfation is a dynamic and complex posttranslational modification process. It can occur at
various positions within the glycosaminoglycan (GAG) backbone and modulates …

Glycosaminoglycans (GAGs) as one major part of the glycocalyx are involved in many
essential biological cell processes, as well as in many courses of diseases. Because of the …

Glycosaminoglycans (GAGs) are an important component of the extracellular matrix as they
influence cell behavior and have been sought for tissue regeneration, biomaterials, and …

The characteristic molecular composition of the different glycosaminoglycans (GAGs) is
related to their role as structural components and regulators of a multitude of functions of …

The increasing prevalence of antibiotic-resistant bacteria portends an impending
postantibiotic age, characterized by diminishing efficacy of common antibiotics and routine …

Highlights•Chondroitin sulfate–dermatan sulfate (CS–DS) chains modulate Wnt/β-catenin
signaling.•Semaphorin 3A and CS–DS in perineuronal nets are involved in neuronal …

Interleukin‐34 (IL‐34) was recently characterized as the M‐CSF “twin” cytokine, regulating
the proliferation/differentiation/survival of myeloid cells. The implication of M‐CSF in …

The brain extracellular matrix (ECM) plays a crucial role in both the developing and adult
brain by providing structural support and mediating cell‐cell interactions. In this review, we …

The remarkable structural heterogeneity of chondroitin sulfate (CS) and dermatan sulfate
(DS) generates biological information that can be unique to each of these …

The glycocalyx surrounds every eukaryotic cell and is a complex mesh of proteins and
carbohydrates. It consists of proteoglycans with glycosaminoglycan side chains, which are …