Pediatric nonalcoholic fatty liver disease (NAFLD): a “growing” problem?

EA Roberts - Journal of hepatology, 2007 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) can affect both adults and children. With the current
worldwide epidemic of pediatric obesity, pediatric NAFLD is increasingly being diagnosed. It …

[HTML][HTML] The genetics of gestational diabetes mellitus: evidence for relationship with type 2 diabetes mellitus

J Robitaille, AM Grant - Genetics in Medicine, 2008 - Elsevier
Gestational diabetes is a major public health problem because of its prevalence, its
associated complications during pregnancy, and its increased risk for type 2 diabetes later in …

Biology of stem cells in human umbilical cord stroma: in situ and in vitro surveys

S Karahuseyinoglu, O Cinar, E Kilic, F Kara… - Stem …, 2007 - academic.oup.com
Cells in the umbilical cord stroma have gained attention in recent years; however,
differentiation to certain lineages in humans has been demonstrated in few studies. Unlike …

[HTML][HTML] Association analysis of ADPRT1, AKR1B1, RAGE, GFPT2 and PAI-1 gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 …

P Prasad, AK Tiwari, KMP Kumar, AC Ammini… - BMC medical …, 2010 - Springer
Background To determine association of nine single nucleotide polymorphisms (SNPs) in
ADP ribosyltransferase-1 (ADPRT1), aldo-keto reductase family 1 member B1 (AKR1B1) …

The contribution of different adipose tissue depots to plasma plasminogen activator inhibitor-1 (PAI-1) levels

SA Barnard, M Pieters, Z De Lange - Blood reviews, 2016 - Elsevier
Increased plasma plasminogen activator inhibitor-1 (PAI-1) level is considered a
mechanistic pathway through which obesity contributes to increased cardiovascular disease …

[HTML][HTML] Impaired fibrinolytic system in ApoE gene-deleted mice with hyperlipidemia augments deep vein thrombosis

JA Diaz, NE Ballard-Lipka, DM Farris, AE Hawley… - Journal of vascular …, 2012 - Elsevier
BACKGROUND: Hyperlipidemia increases the level of blood plasminogen activator inhibitor-
1 (PAI-1) that is responsible for regulating fibrinolysis by inhibiting both urokinase-type …

Evaluation of hypercoagulability in obese children with thrombin generation test and microparticle release: effect of metabolic parameters

Z Şıklar, G Öçal, M Berberoğlu… - Clinical and Applied …, 2011 - journals.sagepub.com
Obesity is associated with a hypercoagulable state. Thrombin generation test (TGT) and
microparticle levels were not studied in obese children extensively. It is aimed to determine …

[HTML][HTML] Genetic factors associated with obesity risks in a Kazakhstani population

M Razbekova, A Issanov, MY Chan… - … , Prevention & Health, 2021 - ncbi.nlm.nih.gov
Objectives There is limited published literature on the genetic risks of chronic inflammatory
related disease (eg, obesity and cardiovascular disease) among the Central Asia …

PAI-1 gene 4G/5G polymorphism, cytokine levels and their relations with metabolic parameters in obese children

ST Kinik, N Özbek, M Yuce, AC Yazici… - Thrombosis and …, 2008 - thieme-connect.com
Obesity is associated with the changes of plasminogen activator inhibitor-1 (PAI-1), tumor
necrosis factor-alpha (TNFα) and transforming growth factor beta (TGFβ) levels. However …

Plasminogen activator inhibitor-1 4G/5G and 5, 10-methylene-tetrahydrofolate reductase C677T polymorphisms in polycystic ovary syndrome

PG Bagos - Molecular human reproduction, 2009 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a heterogeneous condition with unknown etiology and
is considered to be the most common endocrine disorder in women of reproductive age …