Pharmacological effects of cannabidiol by transient receptor potential channels

L Etemad, G Karimi, MS Alavi, A Roohbakhsh - Life Sciences, 2022 - Elsevier
Cannabidiol (CBD), as a major phytocannabinoid of Cannabis sativa, has emerged as a
promising natural compound in the treatment of diseases. Its diverse pharmacological …

Structural and functional comparison of magnesium transporters throughout evolution

GAC Franken, MA Huynen, LA Martínez-Cruz… - Cellular and Molecular …, 2022 - Springer
Abstract Magnesium (Mg2+) is the most prevalent divalent intracellular cation. As co-factor in
many enzymatic reactions, Mg2+ is essential for protein synthesis, energy production, and …

A pentameric TRPV3 channel with a dilated pore

S Lansky, JM Betancourt, J Zhang, Y Jiang, ED Kim… - Nature, 2023 - nature.com
Transient receptor potential (TRP) channels are a large, eukaryotic ion channel superfamily
that control diverse physiological functions, and therefore are attractive drug targets,,,–. More …

Biochemical and physiological plant processes affected by seed treatment with non-thermal plasma

V Mildaziene, A Ivankov, B Sera, D Baniulis - Plants, 2022 - mdpi.com
Among the innovative technologies being elaborated for sustainable agriculture, one of the
most rapidly developing fields relies on the positive effects of non-thermal plasma (NTP) …

Channelling the force to reprogram the matrix: Mechanosensitive ion channels in cardiac fibroblasts

L Stewart, NA Turner - Cells, 2021 - mdpi.com
Cardiac fibroblasts (CF) play a pivotal role in preserving myocardial function and integrity of
the heart tissue after injury, but also contribute to future susceptibility to heart failure. CF …

A review on the role of TRP channels and their potential as drug targets_an insight into the TRP channel drug discovery methodologies

HP Fallah, E Ahuja, H Lin, J Qi, Q He, S Gao… - Frontiers in …, 2022 - frontiersin.org
Transient receptor potential (TRP) proteins are a large group of ion channels that control
many physiological functions in our body. These channels are considered potential …

Transient Receptor Potential (TRP) and thermoregulation in animals: Structural biology and neurophysiological aspects

K Lezama-García, D Mota-Rojas, AMF Pereira… - Animals, 2022 - mdpi.com
Simple Summary In this review, recent discoveries regarding transient receptor potential are
discussed and analyzed to comprehend their role in the thermoregulatory mechanisms of …

Post-injury pain and behaviour: a control theory perspective

B Seymour, RJ Crook, ZS Chen - Nature Reviews Neuroscience, 2023 - nature.com
Injuries of various types occur commonly in the lives of humans and other animals and lead
to a pattern of persistent pain and recuperative behaviour that allows safe and effective …

Calcium carbonate-actuated ion homeostasis perturbator for oxidative damage-augmented Ca2+/Mg2+ interference therapy

J Huang, J He, J Wang, Y Li, Z Xu, L Zhang, Y Kang… - Biomaterials, 2023 - Elsevier
Ion homeostasis distortion through exogenous overload or underload of intracellular ion
species has become an arresting therapeutic approach against malignant tumor …

Evolution of sensory receptors

WA Valencia-Montoya, NE Pierce… - Annual review of cell …, 2024 - annualreviews.org
Sensory receptors are at the interface between an organism and its environment and thus
represent key sites for biological innovation. Here, we survey major sensory receptor …