[HTML][HTML] Neurodevelopmental disorders associated with PSD-95 and its interaction partners
AM Levy, P Gomez-Puertas, Z Tümer - International Journal of Molecular …, 2022 - mdpi.com
The postsynaptic density (PSD) is a massive protein complex, critical for synaptic strength
and plasticity in excitatory neurons. Here, the scaffolding protein PSD-95 plays a crucial role …
and plasticity in excitatory neurons. Here, the scaffolding protein PSD-95 plays a crucial role …
Genetic architecture of ADHD and overlap with other psychiatric disorders and cognition-related phenotypes
Attention-deficit/hyperactivity disorder (ADHD) co-occurs with many other psychiatric
disorders and traits. In this review, we summarize and interpret the existing literature on the …
disorders and traits. In this review, we summarize and interpret the existing literature on the …
Neurodevelopmental disease genes implicated by de novo mutation and copy number variation morbidity
We combined de novo mutation (DNM) data from 10,927 individuals with developmental
delay and autism to identify 253 candidate neurodevelopmental disease genes with an …
delay and autism to identify 253 candidate neurodevelopmental disease genes with an …
[HTML][HTML] Intellectual disability and potassium channelopathies: a systematic review
M Kessi, B Chen, J Peng, Y Tang, E Olatoutou… - Frontiers in …, 2020 - frontiersin.org
Intellectual disability (ID) manifests prior to adulthood as severe limitations to intellectual
function and adaptive behavior. The role of potassium channelopathies in ID is poorly …
function and adaptive behavior. The role of potassium channelopathies in ID is poorly …
[HTML][HTML] Arc regulates transcription of genes for plasticity, excitability and Alzheimer's disease
HW Leung, G Foo, A VanDongen - Biomedicines, 2022 - mdpi.com
The immediate early gene Arc is a master regulator of synaptic function and a critical
determinant of memory consolidation. Here, we show that Arc interacts with dynamic …
determinant of memory consolidation. Here, we show that Arc interacts with dynamic …
Gut microbiome and brain transcriptome analyses reveal the effect of walnut oil in preventing scopolamine-induced cognitive impairment
JY Zheng, T Kang, C Jiang, LK Lin, L Gao, LH Jin… - Food & Function, 2023 - pubs.rsc.org
Walnut Oil (WO) is recognized for its potential to improve cognition, but the mechanisms of
its action related to improving cognitive impairment are not yet clear. In this study, the …
its action related to improving cognitive impairment are not yet clear. In this study, the …
[HTML][HTML] Domain and cell type-specific immunolocalisation of voltage-gated potassium channels in the mouse striatum
B Otuyemi, T Jackson, R Ma, AR Monteiro… - Journal of Chemical …, 2023 - Elsevier
Diverse classes of voltage-gated potassium channels (Kv) are integral to the variety of
electrical activity patterns that distinguish different classes of neurons in the brain. A feature …
electrical activity patterns that distinguish different classes of neurons in the brain. A feature …
[HTML][HTML] Cancer- and behavior-related genes are targeted by selection in the Tasmanian devil (Sarcophilus harrisii)
JN Hubert, T Zerjal, F Hospital - PloS one, 2018 - journals.plos.org
Devil Facial Tumor Disease (DFTD) is an aggressive cancer notorious for its rare etiology
and its impact on Tasmanian devil populations. Two regions underlying an evolutionary …
and its impact on Tasmanian devil populations. Two regions underlying an evolutionary …
[HTML][HTML] miR-9 regulates basal ganglia-dependent developmental vocal learning and adult vocal performance in songbirds
Z Shi, Z Piccus, X Zhang, H Yang, H Jarrell, Y Ding… - Elife, 2018 - elifesciences.org
miR-9 is an evolutionarily conserved miRNA that is abundantly expressed in Area X, a basal
ganglia nucleus required for vocal learning in songbirds. Here, we report that …
ganglia nucleus required for vocal learning in songbirds. Here, we report that …
Kv2. 1 voltage‐gated potassium channels in developmental perspective
J Jędrychowska, V Korzh - Developmental Dynamics, 2019 - Wiley Online Library
Abstract Kv2. 1 voltage‐gated potassium channels consist of two types of α‐subunits:(a)
electrically‐active Kcnb1 α‐subunits and (b) silent or modulatory α‐subunits plus β‐subunits …
electrically‐active Kcnb1 α‐subunits and (b) silent or modulatory α‐subunits plus β‐subunits …