Abstract According to the Alzheimer Association Report (2017), Alzheimer's disease (AD) is
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …

Mounting in vitro and in vivo data suggest that the endocannabinoids anandamide and 2-
arachidonoyl glycerol, as well as some plant and synthetic cannabinoids, have …

Abstract MicroRNA-124 (miR-124) is a brain specific miRNA that is highly expressed in
microglia. The upregulation of miR-124 contributes to M2 polarization of microglia, which is …

Traumatic brain injury represents the leading cause of death in young individuals. Various
animal models have been developed to mimic human closed head injury (CHI). Widely used …

Traumatic brain injury triggers the accumulation of harmful mediators that may lead to
secondary damage,. Protective mechanisms to attenuate damage are also set in motion. 2 …

Experimental autoimmune encephalomyelitis (EAE) is a prototype autoimmune disease
mediated by type 1 helper T (TH1) cells and under the control of regulatory cells,,. Here we …

Cerebral inflammation involves molecular cascades contributing to progressive damage
after traumatic brain injury (TBI). The chemokine CC ligand-2 (CCL2)(formerly monocyte …

There has been an increased focus on the neurological sequelae of repetitive mild traumatic
brain injury (TBI), particularly neurodegenerative syndromes, such as chronic traumatic …

Background and Objective Transcranial low-level laser therapy (LLLT) using near-infrared
light can efficiently penetrate through the scalp and skull and could allow non-invasive …

The mammalian target of rapamycin, commonly known as mTOR, is a serine/threonine
kinase that regulates translation and cell division. mTOR integrates input from multiple …