Super-enhancers and methods of use thereof

RA Young, W Whyte, D Hnisz, J Loven, H Hoke… - US Patent …, 2015 - Google Patents
Provisional application No. 61/718,697, filed on Oct. 25, 2012, provisional application No.
61/799,646, The present invention relates in Some aspects to Super-en filed on Mar. 15 …

Core transcriptional circuitry in human cells and methods of use thereof

V Saint-Andre, BJ Abraham, ZP Fan, TI Lee… - US Patent …, 2022 - Google Patents
US11319591B2 - Core transcriptional circuitry in human cells and methods of use thereof -
Google Patents US11319591B2 - Core transcriptional circuitry in human cells and methods of …

Multifunctional RNA nanoparticles and methods for treating cancer and therapeutic resistant cancer

X Zhang, P Guo - US Patent 11,110,182, 2021 - Google Patents
(57) ABSTRACT RNA nanoparticles functionalized with a HER2-targeting RNA aptamer and
at least one MED1 siRNA for targeted delivery of MED1 siRNA to human cancer cells via …

Super-enhancers and methods of use thereof

D Hnisz, B Abraham, TI Lee, RA Young - US Patent 10,160,977, 2018 - Google Patents
The present invention relates in some aspects to super-enhancers and related
compositions, methods, and agents that are useful for modulating expression of cell type …

Mechanism of resistance to bet bromodomain inhibitors

K Polyak, S Shu, JE Bradner, CY Lin - US Patent 11,666,580, 2023 - Google Patents
US11666580B2 - Mechanism of resistance to bet bromodomain inhibitors - Google Patents
US11666580B2 - Mechanism of resistance to bet bromodomain inhibitors - Google Patents …

Mechanism of resistance to bet bromodomain inhibitors

K Polyak, SHU Shaokun, JE BRANDNER, CY LIN - 2017 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
57984534&utm_source= google_patent&utm_medium= platform_link&utm_campaign …