The macroscopic and microscopic anatomy of the oral cavity is complex and unique in the
human body. Soft-tissue structures are in close interaction with mineralized bone, but also …

Dental caries is a chronic infectious disease resulting from the penetration of oral bacteria
into the enamel and dentin. Microorganisms subsequently trigger inflammatory responses in …

Developments in our understanding of pulp biology and the response of the pulp to the
release of dentine‐bound bioactive growth factors have highlighted that the pulp in mature …

Abstract Background Mitochondrial DNA (mtDNA) is a vital driver of inflammation when it
leaks from damaged mitochondria into the cytosol. mtDNA stress may contribute to cyclic …

The resolution of inflammation is an essential endogenous process that protects host tissues
from an exaggerated chronic inflammatory response. Multiple interactions between host …

The importance of inflammation has been underestimated in pulpal healing, and in the past,
it has been considered only as an undesirable effect. Associated with moderate …

The balance between the immune/inflammatory and regenerative responses in the diseased
pulp is central to the clinical outcome, and this response is unique within the body because …

Alleviating odontoblast inflammation is crucial to control the progression of pulpitis.
Mitochondrial DNA (mtDNA) is a vital driver of inflammation when it leaks from mitochondria …

Ascorbic acid (AA; vitamin C) plays a crucial role in the biosynthesis and secretion of
collagen to produce the organic matrix of hard tissues. Nevertheless, the detailed …

Reactionary dentin formation is an adaptive secretory response mediated by odontoblasts to
moderate dentin injury. The implications of this process for neuroimmune interactions …