Precise regulation of the amplitude and duration of receptor tyrosine kinase (RTK) signaling
is critical for the execution of cellular programs and behaviors. Understanding these control …

Conclusions Immunotherapy was associated with improved OS compared with
chemotherapy in advanced HCC. There are significant disparities in early access to …

Canopy FGF signaling regulator 2 (CNPY2) is a novel angiogenic growth factor. In recent
years, increasing evidence highlights that CNPY2 has important functions in health and …

Background: Revascularization of the heart after myocardial infarction (MI) using growth
factors delivered by hydrogel-based microspheres represents a promising therapeutic …

Myocyte apoptosis is a key determinant of cardiac recovery and prognosis of patients with
acute myocardial infarction (AMI). Tumor necrosis factor (TNF)-like weak inducer of …

Lung cancer is a leading cause of cancer‑related morbidity and mortality worldwide.
Although there are currently various therapeutic strategies including surgery, chemotherapy …

Background This study aimed to explore the role and underlying molecular mechanisms of
long non-coding RNA (lncRNA) LINC00342 in gastric cancer (GC). Methods The expression …

Signal transducer and activator of transcription 3 (STAT3) is known to activate targets
associated with invasion, proliferation, and angiogenesis in a wide variety of cancers. The …

Non-alcoholic fatty liver disease (NAFLD) is highly prevalent, and physical exercise
represents one of the most effective methods to attenuate NAFLD. However, the mechanism …

A forward genetic Sleeping Beauty (SB) insertional mutagenesis screen, followed by high-
throughput transcriptome sequencing, was used to identify driver genes responsible for …