Mass spectrometry approaches to glycomic and glycoproteomic analyses

LR Ruhaak, G Xu, Q Li, E Goonatilleke… - Chemical …, 2018 - ACS Publications
Glycomic and glycoproteomic analyses involve the characterization of oligosaccharides
(glycans) conjugated to proteins. Glycans are produced through a complicated nontemplate …

[HTML][HTML] Recent advances in the mass spectrometry methods for glycomics and cancer

MJ Kailemia, G Xu, M Wong, Q Li… - Analytical …, 2017 - pmc.ncbi.nlm.nih.gov
The review focuses on recent aspects (last three years) of glycosylation analyses that
provide relevant information about cancer. It includes recent development in glycan and …

Clinical application of quantitative glycomics

W Peng, J Zhao, X Dong, A Banazadeh… - Expert review of …, 2018 - Taylor & Francis
Introduction: Aberrant glycosylation has been associated with many diseases. Decades of
research activities have reported many reliable glycan biomarkers of different diseases …

MALDI-TOF/MS analysis of non-invasive human urine and saliva samples for the identification of new cancer biomarkers

C Zambonin, A Aresta - Molecules, 2022 - mdpi.com
Cancer represents a group of heterogeneous diseases that are a leading global cause of
death. Even though mortality has decreased in the past thirty years for different reasons …

Machine learning reveals salivary glycopatterns as potential biomarkers for the diagnosis and prognosis of papillary thyroid cancer

X Ren, J Shu, J Wang, Y Guo, Y Zhang, L Yue… - International Journal of …, 2022 - Elsevier
The diagnosis of thyroid cancer, especially papillary thyroid cancer (PTC), is increasing
rapidly worldwide. In this study, we aimed to study the glycosylation of salivary proteins …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2017–2018

DJ Harvey - Mass Spectrometry Reviews, 2023 - Wiley Online Library
This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization mass spectrometry (MALDI) mass spectrometry …

Diagnosis of hepatocellular carcinoma based on salivary protein glycopatterns and machine learning algorithms

Z Tang, F Zhang, Y Wang, C Zhang, X Li… - Clinical Chemistry and …, 2022 - degruyter.com
Objectives Hepatocellular carcinoma (HCC) is difficult to diagnose early and progresses
rapidly, making it one of the most deadly malignancies worldwide. This study aimed to …

Mass spectrometry-based qualitative and quantitative N-glycomics: An update of 2017–2018

K Xiao, Y Han, H Yang, H Lu, Z Tian - Analytica chimica acta, 2019 - Elsevier
N-glycosylation is one of the most frequently occurring protein post-translational
modifications (PTMs) with broad cellular, physiological and pathological relevance. Mass …

Abnormal Galactosylated–Glycans recognized by Bandeiraea Simplicifolia Lectin I in saliva of patients with breast Cancer

J Yang, X Liu, J Shu, Y Hou, M Chen, H Yu, T Ma… - Glycoconjugate …, 2020 - Springer
Currently, the definitive diagnosis in breast cancer requires biopsy and histopathology, such
the most effective markers are tissue-based. However, the advantages of saliva in collection …

Identification of abnormal fucosylated-glycans recognized by LTL in saliva of HBV-induced chronic hepatitis, cirrhosis, and hepatocellular carcinoma

J Zhang, Y Zhong, P Zhang, H Du, J Shu, X Liu… - …, 2019 - academic.oup.com
The hepatitis B virus (HBV)-induced chronic liver diseases are serious health threats
worldwide. There is evidence to display the alterations of salivary N-linked glycans related to …