Malaria remains a significant threat to global health, and despite concerted efforts to curb the
disease, malaria-related morbidity and mortality increased in recent years. Malaria is caused …

Apicomplexan parasites comprise significant pathogens of humans, livestock and wildlife,
but also represent a diverse group of eukaryotes with interesting and unique cell biology …

The Aurora family of kinases orchestrates chromosome segregation and cytokinesis during
cell division, with precise spatiotemporal regulation of its catalytic activities by distinct protein …

Transmission of malaria-causing parasites to mosquitoes relies on the production of
gametocyte stages and their development into gametes. These stages display various …

Members of Apicomplexa are defined by apical cytoskeletal structures and secretory
organelles, tailored for motility, invasion and egress. Gliding is powered by actomyosin …

Plasmodium falciparum is the causative agent of malaria and remains a pathogen of global
importance. Asexual blood stage replication, via a process called schizogony, is an …

A versatile division of apicomplexan parasites and a dearth of conserved regulators have
hindered the progress of apicomplexan cell cycle studies. While most apicomplexans divide …

Apicomplexan parasites are a group of eukaryotic protozoans with diverse biology that have
affected human health like no other group of parasites. These obligate intracellular parasites …

Faithful chromosome segregation of 8 duplicated haploid genomes into 8 daughter gametes
is essential for male gametogenesis and mosquito transmission of Plasmodium …

The assembly of a functional kinetochore on centromeric chromatin is necessary to connect
chromosomes to the mitotic spindle, ensuring accurate chromosome segregation. This …