Cross-linking mass spectrometry for investigating protein conformations and protein–protein interactions─ a method for all seasons
L Piersimoni, PL Kastritis, C Arlt, A Sinz - Chemical Reviews, 2021 - ACS Publications
Mass spectrometry (MS) has become one of the key technologies of structural biology. In this
review, the contributions of chemical cross-linking combined with mass spectrometry (XL …
review, the contributions of chemical cross-linking combined with mass spectrometry (XL …
Leveraging crosslinking mass spectrometry in structural and cell biology
A Graziadei, J Rappsilber - Structure, 2022 - cell.com
Crosslinking mass spectrometry (crosslinking-MS) is a versatile tool providing structural
insights into protein conformation and protein-protein interactions. Its medium-resolution …
insights into protein conformation and protein-protein interactions. Its medium-resolution …
First community-wide, comparative cross-linking mass spectrometry study
C Iacobucci, C Piotrowski, R Aebersold… - Analytical …, 2019 - ACS Publications
The number of publications in the field of chemical cross-linking combined with mass
spectrometry (XL-MS) to derive constraints for protein three-dimensional structure modeling …
spectrometry (XL-MS) to derive constraints for protein three-dimensional structure modeling …
Cleavable Cross-Linkers and Mass Spectrometry for the Ultimate Task of Profiling Protein–Protein Interaction Networks in Vivo
M Matzinger, K Mechtler - Journal of proteome research, 2020 - ACS Publications
Cross-linking mass spectrometry (XL-MS) has matured into a potent tool to identify protein–
protein interactions or to uncover protein structures in living cells, tissues, or organelles. The …
protein interactions or to uncover protein structures in living cells, tissues, or organelles. The …
Cross-linking/mass spectrometry to get a closer view on protein interaction networks
Just recently, chemical cross-linking combined with mass spectrometry (XL-MS) has
emerged as valuable tool to study protein interaction networks on the system-wide level. The …
emerged as valuable tool to study protein interaction networks on the system-wide level. The …
Toward increased reliability, transparency, and accessibility in cross-linking mass spectrometry
A Leitner, AMJJ Bonvin, CH Borchers, RJ Chalkley… - Structure, 2020 - cell.com
Cross-linking mass spectrometry (MS) has substantially matured as a method over the past
2 decades through parallel development in multiple labs, demonstrating its applicability to …
2 decades through parallel development in multiple labs, demonstrating its applicability to …
Structural dynamics of the E6AP/UBE3A-E6-p53 enzyme-substrate complex
C Sailer, F Offensperger, A Julier, KM Kammer… - Nature …, 2018 - nature.com
Deregulation of the ubiquitin ligase E6AP is causally linked to the development of human
disease, including cervical cancer. In complex with the E6 oncoprotein of human …
disease, including cervical cancer. In complex with the E6 oncoprotein of human …
Structural studies of the eIF4E–VPg complex reveal a direct competition for capped RNA: Implications for translation
L Coutinho de Oliveira, L Volpon… - Proceedings of the …, 2019 - National Acad Sciences
Viruses have transformed our understanding of mammalian RNA processing, including
facilitating the discovery of the methyl-7-guanosine (m7G) cap on the 5′ end of RNAs. The …
facilitating the discovery of the methyl-7-guanosine (m7G) cap on the 5′ end of RNAs. The …
Flipped C-terminal ends of apoA1 promote ABCA1-dependent cholesterol efflux by small HDLs
Y He, C Pavanello, PM Hutchins, C Tang… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: Cholesterol efflux capacity (CEC) predicts cardiovascular disease
independently of high-density lipoprotein (HDL) cholesterol levels. Isolated small HDL …
independently of high-density lipoprotein (HDL) cholesterol levels. Isolated small HDL …
Identification and characterization of the interaction between the methyl-7-guanosine cap maturation enzyme RNMT and the cap-binding protein eIF4E
MJ Osborne, L Volpon, M Memarpoor-Yazdi… - Journal of molecular …, 2022 - Elsevier
The control of RNA metabolism is an important aspect of molecular biology with wide-
ranging impacts on cells. Central to processing of coding RNAs is the addition of the methyl …
ranging impacts on cells. Central to processing of coding RNAs is the addition of the methyl …