Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies
KM Kennedy, MC de Goffau, ME Perez-Muñoz… - Nature, 2023 - nature.com
Whether the human fetus and the prenatal intrauterine environment (amniotic fluid and
placenta) are stably colonized by microbial communities in a healthy pregnancy remains a …
placenta) are stably colonized by microbial communities in a healthy pregnancy remains a …
The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
Fetal meconium does not have a detectable microbiota before birth
KM Kennedy, MJ Gerlach, T Adam, MM Heimesaat… - Nature …, 2021 - nature.com
Microbial colonization of the human intestine impacts host metabolism and immunity;
however, exactly when colonization occurs is unclear. Although many studies have reported …
however, exactly when colonization occurs is unclear. Although many studies have reported …
Human milk oligosaccharides and bacterial profile modulate infant body composition during exclusive breastfeeding
AS Cheema, Z Gridneva, AJ Furst, AS Roman… - International Journal of …, 2022 - mdpi.com
Human milk is a complex and variable ecosystem fundamental to the development of
newborns. This study aimed to investigate relationships between human milk …
newborns. This study aimed to investigate relationships between human milk …
Exclusively breastfed infant microbiota develops over time and is associated with human milk oligosaccharide intakes
AS Cheema, ML Trevenen, BA Turlach… - International Journal of …, 2022 - mdpi.com
Temporal development of maternal and infant microbiomes during early life impacts short-
and long-term infant health. This study aimed to characterize bacterial dynamics within …
and long-term infant health. This study aimed to characterize bacterial dynamics within …
From intrauterine to extrauterine Life—The role of endogenous and exogenous factors in the regulation of the intestinal microbiota community and gut maturation in …
A Socha-Banasiak, M Pawłowska, E Czkwianianc… - Frontiers in …, 2021 - frontiersin.org
Differentiation of the digestive tube and formation of the gut unit as a whole, are regulated by
environmental factors through epigenetic modifications which enhance cellular plasticity …
environmental factors through epigenetic modifications which enhance cellular plasticity …
Gut innervation and enteric nervous system development: a spatial, temporal and molecular tour de force
YN Kang, C Fung, P Vanden Berghe - Development, 2021 - journals.biologists.com
During embryonic development, the gut is innervated by intrinsic (enteric) and extrinsic
nerves. Focusing on mammalian ENS development, in this Review we highlight how …
nerves. Focusing on mammalian ENS development, in this Review we highlight how …
From gut to placenta: understanding how the maternal microbiome models life-long conditions
J Ruiz-Triviño, D Álvarez, ÁP Cadavid J… - Frontiers in …, 2023 - frontiersin.org
The microbiome-defined as the microbiota (bacteria, archaea, lower and higher eukaryotes),
their genomes, and the surrounding environmental conditions-has a well-described range of …
their genomes, and the surrounding environmental conditions-has a well-described range of …
Does the amniotic fluid of mice contain a viable microbiota?
The existence of an amniotic fluid microbiota (ie, a viable microbial community) in mammals
is controversial. Its existence would require a fundamental reconsideration of fetal in utero …
is controversial. Its existence would require a fundamental reconsideration of fetal in utero …
A philosophical perspective on the prenatal in utero microbiome debate
J Walter, MW Hornef - Microbiome, 2021 - Springer
Within the last 6 years, a research field has emerged that focuses on the characterization of
microbial communities in the prenatal intrauterine environment of humans and their putative …
microbial communities in the prenatal intrauterine environment of humans and their putative …